Evidence map›Paper›PMID 40006933›Full record

ArticleViruses2025

Crimean-Congo Hemorrhagic Fever Mimicking HELLP Syndrome in a Pregnant Woman and Her Infant in Kosovo: A Case Report.

Lindita Ajazaj-Berisha, Bahrije Halili, Vera Ndrejaj, Kurtesh Sherifi, Xhevat Jakupi, Simone Priesnitz, Christoph J Hemmer, Salih Ahmeti, Petra Emmerich

Abstract readCase Reports
In one paragraph

Article in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lindita Ajazaj-BerishaInfectious Diseases Hospital, University Clinical Center of Kosovo, 10000 Prishtina, Kosovo.ORCID 0000-0003-3488-7044
Bahrije HaliliInfectious Diseases Hospital, University Clinical Center of Kosovo, 10000 Prishtina, Kosovo.
Vera NdrejajInfectious Diseases Hospital, University Clinical Center of Kosovo, 10000 Prishtina, Kosovo.
Kurtesh SherifiFaculty of Agriculture and Veterinary, University of Prishtina "Hasan Prishtina", 10000 Prishtina, Kosovo.
Xhevat JakupiNational Institute of Public Health of Kosovo, 10000 Pristina, Kosovo.
Simone PriesnitzBundeswehr-Krankenhaus (German Armed Forces Hospital), Lesserstraße 180, 22049 Hamburg, Germany.
Christoph J HemmerDepartment of Tropical Medicine and Infectious Diseases, Center of Internal Medicine, University Medicine Rostock, Ernst-Heydemann-Strasse 6, 18055 Rostock, Germany.ORCID 0000-0001-5650-5639
Salih AhmetiFaculty of Medicine, University "Hasan Prishtina", 10000 Pristina, Kosovo.
Petra EmmerichDepartment of Tropical Medicine and Infectious Diseases, Center of Internal Medicine, University Medicine Rostock, Ernst-Heydemann-Strasse 6, 18055 Rostock, Germany.ORCID 0000-0001-5093-4539

Funding

NONHUMAN PRIMATE MODELS OF ALCOHOL CONSUMPTION AND EXCESSIVE AGGRESSIONZ01AA000277 · NIAAA · ALCOHOL ABUSE AND ALCOHOLISM · PI HIGLEY, JAMES DEE · 1990 to 2006
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German Ministry of Foreign Affairs ZMV-162513AA0277Intramural NIH HHS Z01 AA000277
6 · The paper itself

Abstract

Crimean-Congo hemorrhagic fever (CCHF) is fatal in 10 to 40% of cases. It is caused by CCHF virus (CCHFV). Symptoms include fever, headache, myalgia, and often hemorrhage and other complications. This report shows that CCHF may resemble HELLP syndrome (hemolysis, elevated liver enzymes, low platelets). We report CCHF in a pregnant mother with fever and suspected HELLP syndrome, who survived, and her infant (week 36), who died six days after C-section. The high CCHF viral load and bacterial sepsis may have jointly contributed to the death of the infant. CCHF should be considered as a differential diagnosis of HELLP syndrome in regions where this viral disease is endemic.

Indexed as

HELLP SyndromeHemorrhagic Fever, CrimeanHemorrhagic Fever Virus, Crimean-CongoPregnancy Complications, InfectiousAdultDiagnosis, DifferentialFatal OutcomeFemaleHumansInfant, NewbornKosovoPregnancyViral LoadCCHFCrimean–Congo hemorrhagic feverHELLP syndromeKosovopregnancy

Identifiers

PMID40006933
PMCPMC11860709

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.