ArticleViruses2025
HTLV-1 Infection and Cervicovaginal Susceptibility to High-Risk HPV: Findings from Women Living with HTLV-1 in Salvador, Brazil.
Alisson de Aquino Firmino, Paulo Roberto Tavares Gomes Filho, Juliana Domett Siqueira, Luana Leandro Gois, Giselle Calasans de Souza Costa, Adenilda Lima Lopes Martins, Mariana Lima Drumond, Marcelo Alves Soares, Bernardo Galvão-Castro, Carlos Gustavo Régis da Silva and 1 more
Abstract read
In one paragraphArticle in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
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0citing papers in PubMed
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
11 authors.
Alisson de Aquino FirminoCentro de Atendimento ao Portador de HTLV (CHTLV), Escola Bahiana de Medicina e Saúde Pública (EBMSP), Salvador 40290-000, BA, Brazil.ORCID 0000-0002-1527-8836 Paulo Roberto Tavares Gomes FilhoCentro de Atendimento ao Portador de HTLV (CHTLV), Escola Bahiana de Medicina e Saúde Pública (EBMSP), Salvador 40290-000, BA, Brazil.
Juliana Domett SiqueiraCentro de Pesquisa (CPQ), Instituto Nacional de Câncer (INCA), Rio de Janeiro 20231-050, RJ, Brazil.ORCID 0000-0002-4266-9795 Luana Leandro GoisLaboratório Avançado de Saúde Pública (LASP), Instituto Gonçalo Moniz, Fundação Oswaldo Cruz (FIOCRUZ), Salvador 40296-710, BA, Brazil.ORCID 0000-0002-7538-3558 Giselle Calasans de Souza CostaInstituto de Ciências da Saúde (ICS), Universidade Federal da Bahia (UFBA), Salvador 40110-902, BA, Brazil.
Adenilda Lima Lopes MartinsCentro de Atendimento ao Portador de HTLV (CHTLV), Escola Bahiana de Medicina e Saúde Pública (EBMSP), Salvador 40290-000, BA, Brazil.
Mariana Lima DrumondCentro de Atendimento ao Portador de HTLV (CHTLV), Escola Bahiana de Medicina e Saúde Pública (EBMSP), Salvador 40290-000, BA, Brazil.
Marcelo Alves SoaresCentro de Pesquisa (CPQ), Instituto Nacional de Câncer (INCA), Rio de Janeiro 20231-050, RJ, Brazil.ORCID 0000-0002-9013-2570 Bernardo Galvão-CastroCentro de Atendimento ao Portador de HTLV (CHTLV), Escola Bahiana de Medicina e Saúde Pública (EBMSP), Salvador 40290-000, BA, Brazil.
Carlos Gustavo Régis da SilvaLaboratório Avançado de Saúde Pública (LASP), Instituto Gonçalo Moniz, Fundação Oswaldo Cruz (FIOCRUZ), Salvador 40296-710, BA, Brazil.
Maria Fernanda Rios GrassiCentro de Atendimento ao Portador de HTLV (CHTLV), Escola Bahiana de Medicina e Saúde Pública (EBMSP), Salvador 40290-000, BA, Brazil.ORCID 0000-0002-7356-5569 Funding
Coordenação de Aperfeicoamento de Pessoal de Nível Superior Finance Code 001Fundação de Amparo à Pesquisa do Estado da Bahia BOL0525/2019
6 · The paper itselfAbstract
Persistent oncogenic HPV infection is strongly associated with cervical cancer. Studies have suggested a higher prevalence of HPV in women living with HTLV-1. This study aimed to determine whether HTLV-1 infection is associated with cervicovaginal HPV infection and to characterize HPV types according to oncogenic risk. Vaginal fluid samples were subjected to HPV diagnosis via PCR, and positive samples were subjected to Sanger sequencing and massive sequencing. Papanicolaou smears were examined using light microscopy to identify cell abnormalities. Among the 155 women screened, 79 were HTLV-1-infected and 76 were uninfected. HPV PCR identified 23 positive samples (15/79 vs. 8/76;
Indexed as
Cervix UteriHTLV-I InfectionsHuman T-lymphotropic virus 1PapillomaviridaePapillomavirus InfectionsVaginaAdultBrazilDisease SusceptibilityFemaleHumansMiddle AgedPapanicolaou TestPrevalenceUterine Cervical NeoplasmsYoung Adultcervical cancerHPVHTLV-1
Identifiers
PMID40006895
PMCPMC11860536
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