Evidence map›Paper›PMID 40006718›Full record

ArticleVaccines2025

Adherence to Palivizumab for Respiratory Syncytial Virus Prophylaxis in Romanian Infants.

Andreea Calomfirescu-Avramescu, Adrian Ioan Toma, Claudia Mehedințu, Leonard Năstase, Vlad Dima

Abstract read
In one paragraph

Article in Vaccines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Andreea Calomfirescu-AvramescuFilantropia Clinical Hospital, 011171 Bucharest, Romania.
Adrian Ioan TomaFaculty of Medicine, Titu Maiorescu University, 040441 Bucharest, Romania.
Claudia MehedințuFilantropia Clinical Hospital, 011171 Bucharest, Romania.
Leonard NăstaseObstetrics-Gynecology and Neonatology Department, Carol Davila University of Medicine and Pharmacy, 020956 Bucharest, Romania.
Vlad DimaFilantropia Clinical Hospital, 011171 Bucharest, Romania.ORCID 0000-0001-5969-9205

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn 2022, Romania started an RSV immunoprophylaxis program with Palivizumab for infants at high risk: preterm infants born before 35 weeks of pregnancy, infants born with congenital heart defects, and infants with chronic lung disease. We evaluated treatment adherence from August 2022 to March 2024.

methodWe monitored the increase in the number of patients enrolled in the program and the number of collaborating neonatologists, family doctors, and pediatricians. Adherence to all doses of Palivizumab in enrolled patients was assessed by telephone interviews. The factors contributing to reduced adherence were identified.

resultsBetween August 2022 and March 2024, 1903 patients and 233 specialists were enrolled, a steady increase in both cohorts. The percentage of patients that complete their full sequence of doses decreases along with the number of doses (99% for one dose, 73% for two doses, 47% for three doses, 35% for four doses, and 22% for five doses) due to several factors.

conclusionsThe program remains highly regarded by both physicians and caregivers, demonstrating its effectiveness as a valuable resource for educating parents and facilitating monoclonal antibody administration as a prevention method for RSV.

Indexed as

immunoprophylaxis for RSVpalivizumabrespiratory syncytial virus

Identifiers

PMID40006718
PMCPMC11861343

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.