Evidence map›Paper›PMID 40006577›Full record

ArticlePharmaceutics2025

Thymoquinone-Loaded Chitosan Nanoparticles Combat Testicular Aging and Oxidative Stress Through SIRT1/FOXO3a Activation: An In Vivo and In Vitro Study.

Enas A Kasem, Gehan Hamza, Nagi M El-Shafai, Nora F Ghanem, Shawky Mahmoud, Samy M Sayed, Mohammed Ali Alshehri, Laila A Al-Shuraym, Heba I Ghamry, Magdy E Mahfouz and 1 more

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In one paragraph

Article in Pharmaceutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Modulatory role ofFrontiers in pharmacology · 2025
    Article
  9. Review
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Enas A KasemFaculty of Science, Zoology Department, Kafrelsheikh University, Kafrelsheikh 33516, Egypt.
Gehan HamzaFaculty of Science, Zoology Department, Kafrelsheikh University, Kafrelsheikh 33516, Egypt.
Nagi M El-ShafaiNanotechnology Center, Chemistry Department, Faculty of Science, Kafrelsheikh University, Kafrelsheikh 33516, Egypt.
Nora F GhanemFaculty of Science, Zoology Department, Kafrelsheikh University, Kafrelsheikh 33516, Egypt.
Shawky MahmoudDepartment of Physiology, Faculty of Veterinary Medicine, Kafrelsheikh University, Kafrelsheikh 33516, Egypt.
Samy M SayedDepartment of Economic Entomology and Pesticides, Faculty of Agriculture, Cairo University, Giza 12613, Egypt.ORCID 0000-0002-7002-568X
Mohammed Ali AlshehriDepartment of Biology, Faculty of Science, University of Tabuk, Tabuk 71491, Saudi Arabia.ORCID 0000-0002-0188-1634
Laila A Al-ShuraymDepartment of Biology, College of Science, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia.ORCID 0000-0002-1378-9579
Heba I GhamryNutrition and Food Science, Department of Biology, College of Science, King Khalid University, P.O. Box 960, Abha 61421, Saudi Arabia.
Magdy E MahfouzFaculty of Science, Zoology Department, Kafrelsheikh University, Kafrelsheikh 33516, Egypt.
Mustafa ShukryDepartment of Physiology, Faculty of Veterinary Medicine, Kafrelsheikh University, Kafrelsheikh 33516, Egypt.ORCID 0000-0003-2722-2466

Funding

Princess Nourah bint Abdulrahman University PNURSP2024R365
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

chitosan nanoparticlesD-galoxidative stresstesticular protectionthymoquinone

Identifiers

PMID40006577
PMCPMC11858917

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.