Evidence map›Paper›PMID 40006575›Full record

ReviewPharmaceutics2025

Nanoparticles for Thrombolytic Therapy in Ischemic Stroke: A Systematic Review and Meta-Analysis of Preclinical Studies.

Jesús Prego-Domínguez, Fernando Laso-García, Nuria Palomar-Alonso, María Pérez-Mato, Esteban López-Arias, Antonio Dopico-López, Pablo Hervella, María Gutiérrez-Fernández, María Alonso de Leciñana, Ester Polo and 4 more

Abstract readReview
In one paragraph

Review in Pharmaceutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Jesús Prego-DomínguezHead of Epidemiologic Surveillance Service, Public Health General Directorate, Consellería de Sanidade, 15703 Santiago de Compostela, Spain.
Fernando Laso-GarcíaNeurological Sciences and Cerebrovascular Research Laboratory, Department of Neurology and Stroke Centre, Neurology and Cerebrovascular Disease Group, Neuroscience Area La Paz Institute for Health Research-idiPAZ, La Paz University Hospital-Universidad Autónoma de Madrid, 28049 Madrid, Spain.
Nuria Palomar-AlonsoTranslational Stroke Laboratory (TREAT), Clinical Neurosciences Research Laboratory (LINC), Health Research Institute of Santiago de Compostela (IDIS), 15706 Santiago de Compostela, Spain.
María Pérez-MatoTranslational Stroke Laboratory (TREAT), Clinical Neurosciences Research Laboratory (LINC), Health Research Institute of Santiago de Compostela (IDIS), 15706 Santiago de Compostela, Spain.
Esteban López-AriasTranslational Stroke Laboratory (TREAT), Clinical Neurosciences Research Laboratory (LINC), Health Research Institute of Santiago de Compostela (IDIS), 15706 Santiago de Compostela, Spain.ORCID 0000-0002-0242-3600
Antonio Dopico-LópezTranslational Stroke Laboratory (TREAT), Clinical Neurosciences Research Laboratory (LINC), Health Research Institute of Santiago de Compostela (IDIS), 15706 Santiago de Compostela, Spain.
Pablo HervellaNeuroimaging and Biotechnology Laboratory (NOBEL), Clinical Neurosciences Research Laboratory (LINC), Health Research Institute of Santiago de Compostela (IDIS), Hospital Clínico Universitario, Rúa Travesa da Choupana s/n, 15706 Santiago de Compostela, Spain.ORCID 0000-0003-1249-6333
María Gutiérrez-FernándezNeurological Sciences and Cerebrovascular Research Laboratory, Department of Neurology and Stroke Centre, Neurology and Cerebrovascular Disease Group, Neuroscience Area La Paz Institute for Health Research-idiPAZ, La Paz University Hospital-Universidad Autónoma de Madrid, 28049 Madrid, Spain.
María Alonso de LeciñanaNeurological Sciences and Cerebrovascular Research Laboratory, Department of Neurology and Stroke Centre, Neurology and Cerebrovascular Disease Group, Neuroscience Area La Paz Institute for Health Research-idiPAZ, La Paz University Hospital-Universidad Autónoma de Madrid, 28049 Madrid, Spain.ORCID 0000-0002-4302-6580
Ester PoloCenter for Research in Biological Chemistry and Molecular Materials (CiQUS), University of Santiago de Compostela (USC), 15705 Santiago de Compostela, Spain.
Beatriz PelazCenter for Research in Biological Chemistry and Molecular Materials (CiQUS), University of Santiago de Compostela (USC), 15705 Santiago de Compostela, Spain.
Pablo Del PinoCenter for Research in Biological Chemistry and Molecular Materials (CiQUS), University of Santiago de Compostela (USC), 15705 Santiago de Compostela, Spain.
Francisco CamposTranslational Stroke Laboratory (TREAT), Clinical Neurosciences Research Laboratory (LINC), Health Research Institute of Santiago de Compostela (IDIS), 15706 Santiago de Compostela, Spain.ORCID 0000-0001-8665-1039
Clara Correa-PazNeurological Sciences and Cerebrovascular Research Laboratory, Department of Neurology and Stroke Centre, Neurology and Cerebrovascular Disease Group, Neuroscience Area La Paz Institute for Health Research-idiPAZ, La Paz University Hospital-Universidad Autónoma de Madrid, 28049 Madrid, Spain.

Funding

Euronanomed III Call Euronanomed2020_143Instituto de Salud Carlos III AC20/00031Instituto de Salud Carlos III CD23/00005Instituto de Salud Carlos III ICI19/00032Instituto de Salud Carlos III PI20/01014Instituto de Salud Carlos III RD21/0006/0003Xunta de Galicia IN607A2022/02
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cell membrane-derived nanomedicinesischemic strokemeta-analysisnanoparticlesrtPAthrombolysis

Identifiers

PMID40006575
PMCPMC11859612

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.