Evidence map›Paper›PMID 40006567›Full record

ArticlePharmaceutics2025

A Novel LC-MS/MS Method for the Measurement of Elexacaftor, Tezacaftor and Ivacaftor in Plasma, Dried Plasma Spot (DPS) and Whole Blood in Volumetric Absorptive Microsampling (VAMS) Devices.

Federica Pigliasco, Alessia Cafaro, Sebastiano Barco, Federico Cresta, Rosaria Casciaro, Nicoletta Pedemonte, Francesca Mattioli, Carlo Castellani, Giuliana Cangemi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Federica PigliascoUnit of Biochemistry, Pharmacology and Newborn Screening, Central Laboratory of Analysis, IRCCS Istituto Giannina Gaslini, 16147 Genoa, Italy.ORCID 0000-0002-2631-8610
Alessia CafaroUnit of Biochemistry, Pharmacology and Newborn Screening, Central Laboratory of Analysis, IRCCS Istituto Giannina Gaslini, 16147 Genoa, Italy.ORCID 0000-0003-1132-1267
Sebastiano BarcoUnit of Biochemistry, Pharmacology and Newborn Screening, Central Laboratory of Analysis, IRCCS Istituto Giannina Gaslini, 16147 Genoa, Italy.ORCID 0000-0002-1148-427X
Federico CrestaCystic Fibrosis Center, IRCCS Istituto Giannina Gaslini, 16147 Genoa, Italy.ORCID 0000-0002-2483-5374
Rosaria CasciaroCystic Fibrosis Center, IRCCS Istituto Giannina Gaslini, 16147 Genoa, Italy.
Nicoletta PedemonteUOC Genetica Medica, IRCCS Istituto Giannina Gaslini, 16147 Genoa, Italy.ORCID 0000-0002-5161-1720
Francesca MattioliPharmacology & Toxicology Unit, Department of Internal Medicine, University of Genoa, Viale Benedetto XV 2, 16132 Genoa, Italy.ORCID 0000-0001-8460-0262
Carlo CastellaniCystic Fibrosis Center, IRCCS Istituto Giannina Gaslini, 16147 Genoa, Italy.ORCID 0000-0003-1916-0963
Giuliana CangemiUnit of Biochemistry, Pharmacology and Newborn Screening, Central Laboratory of Analysis, IRCCS Istituto Giannina Gaslini, 16147 Genoa, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CFTR modulatorscystic fibrosisliquid chromatograph–tandem mass spectrometrymicrosamplingpediatric pharmacology

Identifiers

PMID40006567
PMCPMC11859332

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.