Evidence map›Paper›PMID 40006554›Full record

ArticlePharmaceutics2025

Ustekinumab Drug Clearance Is Better Associated with Disease Control than Serum Trough Concentrations in a Prospective Cohort of Inflammatory Bowel Disease.

Andres J Yarur, Thierry Dervieux, Ryan Ungaro, Elizabeth A Spencer, Alexandra Bruss, Lizbeth Nunez, Brandon Berens, Séverine Vermeire, Zhigang Wang, John C Panetta and 2 more

Abstract read
In one paragraph

Article in Pharmaceutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Andres J YarurCedars Sinai Medical Center, Los Angeles, CA 90001, USA.
Thierry DervieuxPrometheus Laboratories, San Diego, CA 92121, USA.
Ryan UngaroMount Sinai Medical Center, New York, NY 10029, USA.
Elizabeth A SpencerMount Sinai Medical Center, New York, NY 10029, USA.
Alexandra BrussMedical College of Wisconsin, Milwaukee, WI 53226, USA.
Lizbeth NunezMedical College of Wisconsin, Milwaukee, WI 53226, USA.
Brandon BerensMedical College of Wisconsin, Milwaukee, WI 53226, USA.
Séverine VermeireKU Leuven, Department of Gastroenterology, Pharmacometrics, 3000 Leuven, Belgium.ORCID 0000-0001-9942-3019
Zhigang WangKU Leuven, Department of Gastroenterology, Pharmacometrics, 3000 Leuven, Belgium.ORCID 0000-0001-6415-2044
John C PanettaSt Jude Children's Research Hospital, Memphis, TN 38016, USA.
Erwin DreesenKU Leuven, Department of Gastroenterology, Pharmacometrics, 3000 Leuven, Belgium.ORCID 0000-0002-0785-2930
Marla C DubinskyMount Sinai Medical Center, New York, NY 10029, USA.

Funding

Prometheus NA
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

clearanceinflammatory bowel diseasepharmacokineticstherapeutic drug monitoringustekinumab

Identifiers

PMID40006554
PMCPMC11859385

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.