ReviewSensors (Basel, Switzerland)2025
A Comprehensive Review of Advanced Lactate Biosensor Materials, Methods, and Applications in Modern Healthcare.
Review in Sensors (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- A Flexible Wearable Multisensing Patch Integrating SWCNT-PtNPs Nanocomposites for Non-Invasive Clinical Biomarkers Monitoring in Sweat.Polymers · 2026Article
- A Hitchhiker's Guide to Physical and Cognitive Effort.Sports medicine (Auckland, N.Z.) · 2026Review
- Swab-based colorimetric determination of tear lactate using lactate oxidase-copper hybrid nanoflowers.Mikrochimica acta · 2026Article
- Wearable Sensors for Health Monitoring.Biosensors · 2026Review
- Development of a biosensor for spectrophotometric determination of L-lactate in artificial saliva.BMC chemistry · 2026Article
- Conducting Polymers for Electrochemical Sensing: From Materials and Metrology to Intelligent and Sustainable Biointerfaces.Sensors (Basel, Switzerland) · 2026Review
- Covalent and Site-Specific Immobilization of a Fluorogenic Sensor Protein on Cellulose-Based Paper for Detection of Lactate in Cell Culture Media.Biosensors · 2025Article
- Biosensor-Integrated Tibial Components in Total Knee Arthroplasty: A Narrative Review of Innovations, Challenges, and Translational Frontiers.Bioengineering (Basel, Switzerland) · 2025Review
- 3D Printing Assisted Wearable and Implantable Biosensors.Biosensors · 2025Review
- Dual-mode detection of lactic acid using B, N-doped carbon dots with peroxidase-mimicking activity for diabetes monitoring.Mikrochimica acta · 2025Article
- Thermoplastics for Clear Aligners: A Review.Polymers · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
Lactate is a key metabolite in cellular respiration, and elevated levels usually indicate tissue hypoxia or metabolic dysregulation. The real-time detection of lactate levels is particularly important in situations such as exercise, shock, severe trauma, and tissue injury. Conventional lactate assays are insufficient to address today's complex and variable testing environments, and thus, there is an urgent need for highly sensitive biosensors. This review article provides an overview of the concept and composition of electrochemical lactate biosensors, as well as their recent advances. Comparisons of popular studies on enzymatic and non-enzymatic lactate sensors, the surface-related materials used for modifications to electrochemical lactate biosensors, and the detection methods commonly used for sensors are discussed separately. In addition, advances in implantable and non-implantable miniaturized lactate sensors are discussed, emphasizing their application for continuous real-time monitoring. Despite their potential, challenges such as non-specific binding, biomaterial interference, and biorecognition element stability issues remain during practical applications. Future research should aim to improve sensor design, biocompatibility, and integration with advanced signal processing techniques. With continued innovation, lactate sensors are expected to revolutionize personalized medicine, helping clinicians to increase treatment efficiency and improve the experience of their use.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.