ArticleSensors (Basel, Switzerland)2025
Real-Time Detection of Human Growth Hormone Based on Nanoporous Anodic Alumina Interferometric Biosensor.
Article in Sensors (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Nanoporous-based biomaterials in biomedical applications: from fundamentals and biosensing to drug delivery, wound healing, and tissue engineering.Nanoscale advances · 2026Review
- Proteoformics-driven new concept of human growth hormone in clinical endocrinology.Frontiers in endocrinology · 2026Review
- Minimizing Color Difference in AAO-Based Coatings for Urban Camouflage.Nanomaterials (Basel, Switzerland) · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Human growth hormone (hGH) is a polypeptide hormone that is synthesized and secreted by the anterior pituitary gland, whose excess is linked to acromegaly-causing pituitary adenomas while deficiencies are linked to disorders including short stature and Turner's syndrome. This study investigates the real-time biosensing of hGH using a microfluidic optical biosensor based on reflectometric interferometry Fourier spectroscopy (RIFTS). The biosensing platform is based on a monolayer of nanoporous anodic alumina (NAA) fabricated following the two-step anodization method to produce pore sizes between 30 and 35 nm. The sensitivity of the nanostructure is improved by increasing the effective surface area by widening the pores to about 45 nm. NAA structures are then functionalized to make them selective to hGH. The sensing performance of the system shows a linear detection range from 12.5 µg/mL to 100 µg/mL with a detection limit of 10.6 µg/mL. This biosensing platform demonstrates the capability to detect high concentrations of human growth hormone using a cost-effective, fast, and portable biosensing system.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.