Evidence map›Paper›PMID 40006190›Full record

ArticlePolymers2025

The Effect of Alginate/Hyaluronic Acid Proportion on Semi-Interpenetrating Hydrogel Properties for Articular Cartilage Tissue Engineering.

Izar Gorroñogoitia, Sheila Olza, Ana Alonso-Varona, Ane Miren Zaldua

Abstract read
In one paragraph

Article in Polymers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Izar GorroñogoitiaLeartiker S. Coop., 48270 Makina-Xemein, Spain.ORCID 0000-0002-2383-2892
Sheila OlzaFaculty of Medicine and Nursing, University of the Basque Country (UPV/EHU), 48940 Leioa, Spain.ORCID 0000-0002-5358-3241
Ana Alonso-VaronaFaculty of Medicine and Nursing, University of the Basque Country (UPV/EHU), 48940 Leioa, Spain.ORCID 0000-0002-9386-0047
Ane Miren ZalduaLeartiker S. Coop., 48270 Makina-Xemein, Spain.ORCID 0000-0002-9756-0738

Funding

University of The Basque Country UPV/EHU GIU21/054 and PES50/21
6 · The paper itself

Abstract

One of the emergent regenerative treatments for the restoration of the articular cartilage is tissue engineering (TE), in which hydrogels can functionally imitate the extracellular matrix (ECM) of the native tissue and create an optimal microenvironment for the restoration of the defective tissue. Hyaluronic acid (HA) is known for its potential in the field of TE as a regenerative material for many tissues. It is one of the major components of the articular cartilage ECM contributing to cell proliferation and migration. HA is the only non-sulphated glycosaminoglycan (GAG). However, herein, we use a HA presenting a high amount of sulphated glycosaminoglycans (sGAGs), altering the intrinsic properties of the material particularly in terms of biological response. Alginate (Alg) is another polysaccharide widely used in TE that allows stiff and stable hydrogels to be obtained when crosslinked with CaCl

Indexed as

alginatebioprintinghyaluronic acidhydrogelscaffold

Identifiers

PMID40006190
PMCPMC11859035

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.