Evidence map›Paper›PMID 40006082›Full record

ArticlePharmaceuticals (Basel, Switzerland)2025

Design, Synthesis, and Mechanistic Anticancer Evaluation of New Pyrimidine-Tethered Compounds.

Farida Reymova, Belgin Sever, Edanur Topalan, Canan Sevimli-Gur, Mustafa Can, Amaç Fatih Tuyun, Faika Başoğlu, Abdulilah Ece, Masami Otsuka, Mikako Fujita and 2 more

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Farida ReymovaDepartment of Bioengineering Sciences, Izmir Katip Celebi University, Izmir 35620, Türkiye.
Belgin SeverDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Anadolu University, Eskisehir 26470, Türkiye.ORCID 0000-0003-4847-9711
Edanur TopalanDepartment of Molecular Biology and Genetics, Koc University, Istanbul 34450, Türkiye.
Canan Sevimli-GurDepartment of Basic Pharmaceutical Sciences, Faculty of Pharmacy, Izmir Katip Celebi University, Izmir 35620, Türkiye.ORCID 0000-0002-2210-5925
Mustafa CanDepartment of Bioengineering Sciences, Izmir Katip Celebi University, Izmir 35620, Türkiye.ORCID 0000-0002-1749-8293
Amaç Fatih TuyunDepartment of Chemistry, Faculty of Science, Istanbul University, Fatih, Istanbul 34126, Türkiye.ORCID 0000-0001-5698-1109
Faika BaşoğluDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, European University of Lefke, Northern Cyprus, TR-10, Mersin 99800, Türkiye.ORCID 0000-0002-4890-3124
Abdulilah EceDepartment of Medical Biochemistry, Faculty of Medicine, Biruni University, İstanbul 34015, Türkiye.ORCID 0000-0002-3087-5145
Masami OtsukaMedicinal and Biological Chemistry Science Farm Joint Research Laboratory, Faculty of Life Sciences, Kumamoto University, Kumamoto 862-0973, Japan.
Mikako FujitaMedicinal and Biological Chemistry Science Farm Joint Research Laboratory, Faculty of Life Sciences, Kumamoto University, Kumamoto 862-0973, Japan.ORCID 0000-0001-6705-4052
Hasan DemirciDepartment of Molecular Biology and Genetics, Koc University, Istanbul 34450, Türkiye.ORCID 0000-0002-9135-5397
Halilibrahim CiftciDepartment of Bioengineering Sciences, Izmir Katip Celebi University, Izmir 35620, Türkiye.ORCID 0000-0002-9796-7669

Funding

Scientific and Technological Research Council of Turkey 122Z775
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

apoptosisbreast cancerchalconeEGFRinduced fit dockinglung cancermolecular dynamics simulationpyrazolinepyrimidinethiazole

Identifiers

PMID40006082
PMCPMC11859636

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.