Evidence map›Paper›PMID 40005977›Full record

ArticlePharmaceuticals (Basel, Switzerland)2025

Intranasal Human-Recombinant Nerve Growth Factor Enhances Motor and Cognitive Function Recovery in a Child with Severe Traumatic Brain Injury.

Lorenzo Di Sarno, Lavinia Capossela, Serena Ferretti, Luigi Manni, Marzia Soligo, Susanna Staccioli, Eleonora Napoli, Riccardo Burattini, Antonio Gatto, Antonio Chiaretti

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lorenzo Di SarnoInstitute of Pediatrics, Fondazione Policlinico A. Gemelli IRCCS, 00168 Rome, Italy.ORCID 0000-0002-4837-9297
Lavinia CaposselaInstitute of Pediatrics, Fondazione Policlinico A. Gemelli IRCCS, 00168 Rome, Italy.
Serena FerrettiInstitute of Pediatrics, Fondazione Policlinico A. Gemelli IRCCS, 00168 Rome, Italy.
Luigi ManniIstituto di Farmacologia Traslazionale, Consiglio Nazionale delle Ricerche (CNR), 00133 Rome, Italy.ORCID 0000-0001-7844-6836
Marzia SoligoIstituto di Farmacologia Traslazionale, Consiglio Nazionale delle Ricerche (CNR), 00133 Rome, Italy.ORCID 0000-0002-1420-0914
Susanna StaccioliDipartimento di Neuroriabilitazione Intensiva, Ospedale Pediatrico "Bambino Gesù", 00050 Rome, Italy.
Eleonora NapoliUnit of Neurorehabilitation, Department of Neurosciences, Bambino Gesù Children's Hospital, IRCCS, 00050 Rome, Italy.ORCID 0000-0002-1436-2825
Riccardo BurattiniDipartimento di Neuroriabilitazione Intensiva, Ospedale Pediatrico "Bambino Gesù", 00050 Rome, Italy.ORCID 0009-0004-8639-5097
Antonio GattoInstitute of Pediatrics, Fondazione Policlinico A. Gemelli IRCCS, 00168 Rome, Italy.ORCID 0000-0002-8778-9328
Antonio ChiarettiInstitute of Pediatrics, Fondazione Policlinico A. Gemelli IRCCS, Università Cattolica Sacro Cuore, 00168 Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

brain injurychildrencognitive functionsdiffuse axonal injuryintranasal administrationnerve growth factor

Identifiers

PMID40005977
PMCPMC11858550

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.