Evidence map›Paper›PMID 40005861›Full record

ArticleVeterinary sciences2025

Development and Efficacy Evaluation of a Novel Nanoparticle-Based Hemagglutination Inhibition Assay for Serological Studies of Porcine Epidemic Diarrhea Virus.

Fengyan Liang, Wenyue Qiao, Mengjia Zhang, Zhangtiantian Hu, Shan Zhao, Qigui Yan, Wentao Li, Yifei Lang

Abstract read
In one paragraph

Article in Veterinary sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Fengyan LiangCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Wenyue QiaoCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Mengjia ZhangNational Key Laboratory of Agricultural Microbiology, Hubei Hongshan Laboratory, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China.
Zhangtiantian HuCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Shan ZhaoCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Qigui YanCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.
Wentao LiNational Key Laboratory of Agricultural Microbiology, Hubei Hongshan Laboratory, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, China.ORCID 0000-0002-7114-762X
Yifei LangCollege of Veterinary Medicine, Sichuan Agricultural University, Chengdu 611130, China.

Funding

Joint Funds of Science Technology and Education of Sichuan Province 2024NSFSC2063National Natural Science Foundation of China 32473007
6 · The paper itself

Abstract

Porcine epidemic diarrhea virus (PEDV) is a major pathogen that causes serious economic losses to the swine industry. To aid PEDV clinical diagnosis and vaccine development, sensitive and precise serological methods are demanded for rapid detection of (neutralizing) antibodies. Aiming for the development of a novel virus-free hemagglutination inhibition (HI) assay, the N-terminal region of the PEDV S1 subunit, encompassing the sialic acid-binding motif, was first expressed as an Fc-fusion protein with a C-terminal Spy Tag (S1

Indexed as

hemagglutination inhibition assaynanoparticleporcine epidemic diarrhea virusS10A proteinserology

Identifiers

PMID40005861
PMCPMC11861430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.