Evidence map›Paper›PMID 40005839›Full record

ArticleVeterinary sciences2025

Impact of Calcium Propionate Supplementation on the Lactation Curve and Milk Metabolomic Analysis on Rambouillet Ewes.

Luis Fernando Pérez Segura, Hector A Lee-Rangel, Rogelio Flores Ramirez, Juan Carlos García-López, Gregorio Álvarez-Fuentes, Anayeli Vázquez Valladolid, Pedro A Hernández-García, Octavio Negrete Sanchez, Juan Antonio Rendon Huerta

Abstract read
In one paragraph

Article in Veterinary sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Luis Fernando Pérez SeguraInstituto de Investigaciones en Zonas Desérticas, Facultad de Agronomía y Veterinaria, Centro de Biociencias, Universidad Autónoma de San Luis Potosí, San Luis Potosí 78321, Mexico.
Hector A Lee-RangelInstituto de Investigaciones en Zonas Desérticas, Facultad de Agronomía y Veterinaria, Centro de Biociencias, Universidad Autónoma de San Luis Potosí, San Luis Potosí 78321, Mexico.ORCID 0000-0001-6146-5790
Rogelio Flores RamirezCoordinación para la Innovación y Aplicación de la Ciencia y la Tecnología (CIACYT), Universidad Autónoma de San Luis Potosí, Av. Sierra Leona núm. 550-2ª, Lomas de San Luis, San Luis Potosí 78210, Mexico.ORCID 0000-0003-2263-6280
Juan Carlos García-LópezInstituto de Investigaciones en Zonas Desérticas, Facultad de Agronomía y Veterinaria, Centro de Biociencias, Universidad Autónoma de San Luis Potosí, San Luis Potosí 78321, Mexico.ORCID 0000-0002-6922-6898
Gregorio Álvarez-FuentesInstituto de Investigaciones en Zonas Desérticas, Facultad de Agronomía y Veterinaria, Centro de Biociencias, Universidad Autónoma de San Luis Potosí, San Luis Potosí 78321, Mexico.
Anayeli Vázquez ValladolidInstituto de Investigaciones en Zonas Desérticas, Facultad de Agronomía y Veterinaria, Centro de Biociencias, Universidad Autónoma de San Luis Potosí, San Luis Potosí 78321, Mexico.
Pedro A Hernández-GarcíaCentro Universitario Amecameca, Universidad Autónoma del Estado de México, Amecameca 56900, Mexico.ORCID 0000-0002-3820-4370
Octavio Negrete SanchezInstituto de Investigaciones en Zonas Desérticas, Facultad de Agronomía y Veterinaria, Centro de Biociencias, Universidad Autónoma de San Luis Potosí, San Luis Potosí 78321, Mexico.ORCID 0000-0002-4026-1518
Juan Antonio Rendon HuertaInstituto de Investigaciones en Zonas Desérticas, Facultad de Agronomía y Veterinaria, Centro de Biociencias, Universidad Autónoma de San Luis Potosí, San Luis Potosí 78321, Mexico.ORCID 0000-0003-1287-4816

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In lactating ewes, energy demand increases for milk production, reserve mobilizations, and body weight maintenance. For reconversion to energy, ruminants require ruminal propionate production because it is the most predominant substrate for gluconeogenesis and one of the most relevant pathways since it allows an adequate supply of glucose. Calcium propionate supplementation is an alternative to increase glucose production by an external additive. Thus, the objective was to evaluate the effect of calcium propionate (CaPr) on milk production and milk metabolomic profile on lactating ewes. Sixteen Rambouillet (65.3 ± 6.2 kg BW; three years old) were randomly assigned one of two experimental treatments: (a) basal diet without supplementation (CP/0S) and (b) basal diet + 30 g d

Indexed as

ewesgluconeogenic precursormetabolomic analysismilk compoundmilk performance

Identifiers

PMID40005839
PMCPMC11860503

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.