Evidence map›Paper›PMID 40005837›Full record

ArticleVeterinary sciences2025

Effects of Milk Thistle Extract Supplementation on Performance, Egg Quality, and Liver Pathology of Laying Hens' Fed Diets Lacking Supplemental Choline Chloride.

Fotis Gousias, Ioanna Stylianaki, Ilias Giannenas, Theodoros Kallitsis, Nikolaos Papaioannou, Efstratios Chaitidis, Clare Squires, Georgios Arsenos, Vasilios Tsiouris, Georgios A Papadopoulos

Abstract read
In one paragraph

Article in Veterinary sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Effects ofVeterinary sciences · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Fotis GousiasLaboratory of Animal Husbandry, Faculty of Veterinary Medicine, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece.ORCID 0009-0001-8636-650X
Ioanna StylianakiLaboratory of Pathology, Faculty of Veterinary Medicine, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece.
Ilias GiannenasLaboratory of Nutrition, Faculty of Veterinary Medicine, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece.ORCID 0000-0003-3145-3734
Theodoros KallitsisLaboratory of Animal Husbandry, Faculty of Veterinary Medicine, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece.
Nikolaos PapaioannouLaboratory of Pathology, Faculty of Veterinary Medicine, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece.
Efstratios ChaitidisLaboratory of Pathology, Faculty of Veterinary Medicine, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece.
Clare SquiresLaboratory of Animal Husbandry, Faculty of Veterinary Medicine, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece.
Georgios ArsenosLaboratory of Animal Husbandry, Faculty of Veterinary Medicine, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece.ORCID 0000-0003-3224-5128
Vasilios TsiourisUnit of Avian Medicine, Clinic of Farm Animals, Faculty of Veterinary Medicine, Aristotle University of Thessaloniki, 546 27 Thessaloniki, Greece.ORCID 0000-0003-2970-2463
Georgios A PapadopoulosLaboratory of Animal Husbandry, Faculty of Veterinary Medicine, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece.ORCID 0000-0003-0958-4121

Funding

European Regional Development Fund and Greek National Funds through the Operational Pro-gram of Central Macedonia 2021-2027 KMP6-0219669
6 · The paper itself

Abstract

The current study evaluated the effects of milk thistle extract supplementation in laying hens' fed diets lacking choline chloride addition. A total of 60 Isa-brown laying hens were randomly allocated into T1: control diet, 0% extract supplementation; T2: control diet with 1% extract; T3: control diet with 2.5% extract; and T4: control diet with 4% extract. Egg quality parameters, yolk lipid oxidation, malondialdehyde (MDA) content, and fatty acid profile were assessed. Livers were examined grossly and histologically to evaluate hepatocellular lesions such as vacuolization (lipidosis), reticular stromal architecture, the amount of collagenous connective tissue, and vascular wall changes. Groups T3 and T4 showed darker yolks compared to both control group and T2 (

Indexed as

egg qualitylaying hensliver healthmilk thistle

Identifiers

PMID40005837
PMCPMC11860362

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.