Evidence map›Paper›PMID 40005805›Full record

ReviewMicroorganisms2025

Implementation of Antimicrobial Stewardship Programs in Saudi Arabia: A Systematic Review.

Abdullah A Alshehri, Jehad A Aldali, Maysoon A Abdelhamid, Alaa A Alanazi, Ratal B Alhuraiz, Lamya Z Alanazi, Meaad A Alshmrani, Alhanouf M Alqahtani, Maha I Alrshoud, Reema F Alharbi

Abstract readReview
In one paragraph

Review in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Abdullah A AlshehriDepartment of Clinical Pharmacy, College of Pharmacy, Taif University, Al Huwaya, Taif 21944, Saudi Arabia.ORCID 0000-0002-4785-4551
Jehad A AldaliDepartment of Pathology, College of Medicine, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 13317, Saudi Arabia.ORCID 0000-0001-9754-3826
Maysoon A AbdelhamidCollege of Medicine, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 13317, Saudi Arabia.
Alaa A AlanaziCollege of Medicine, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 13317, Saudi Arabia.
Ratal B AlhuraizCollege of Medicine, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 13317, Saudi Arabia.
Lamya Z AlanaziCollege of Medicine, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 13317, Saudi Arabia.
Meaad A AlshmraniCollege of Medicine, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 13317, Saudi Arabia.
Alhanouf M AlqahtaniCollege of Medicine, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 13317, Saudi Arabia.
Maha I AlrshoudCollege of Medicine, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 13317, Saudi Arabia.
Reema F AlharbiCollege of Medicine, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 13317, Saudi Arabia.

Funding

This work was supported and funded by the Deanship of Scientific Research at Imam Mohammad Ibn Saud Islamic University (IMSIU) grant number IMSIU-DDRSP2501
6 · The paper itself

Abstract

backgroundAntimicrobial resistance has highlighted the need for effective infectious disease strategies. Antimicrobial stewardship programs (ASPs) may reduce antibiotic resistance, adverse reactions, and treatment failures. This systematic review examines ASPs in Saudi Arabia, assessing their efficacy, challenges, and outcomes to improve antimicrobial use and patient care.

methodsSearches were carried out in the Ovid, MEDLINE, Embase, PsycInfo, Scopus, and Web of Science Core Collection databases for studies published from 2007 to July 2024, in Saudi Arabia, following the PRISMA guidelines. Studies that assessed ASPs' implementation, effectiveness, and outcomes in hospital settings were included.

resultsOut of the 6080 titles identified, 14 studies met the inclusion criteria, covering different regions of the country, including Riyadh, Jeddah, Dhahran, Makkah, Al-Kharj, and a multi-regional study in Qassim and Riyadh. Various interventions were implemented by the ASPs, such as educational programs, audit and feedback, switching from intravenous to oral administration, and enhanced policies. These interventions collectively led to a decrease in the overall antimicrobial consumption and cost, and a reduction in cases with multidrug-resistant bacteria.

conclusionsThe findings of this review highlight the positive impact of ASPs in Saudi Arabia. However, addressing challenges such as data limitations and training gaps is essential to enhance their effectiveness. Expanding education and refining implementation strategies are crucial for ensuring their long-term success.

Indexed as

antimicrobial resistanceantimicrobial stewardship programsimplementationinfection controlSaudi Arabia

Identifiers

PMID40005805
PMCPMC11858812

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.