Evidence map›Paper›PMID 40005763›Full record

ReviewMicroorganisms2025

Antischistosomal Potential of Animal-Derived Natural Products and Compounds.

Agatha Fischer-Carvalho, Tereza Cristina Taveira-Barbosa, Sergio Verjovski-Almeida, Simone Haeberlein, Murilo Sena Amaral

Abstract readReview
In one paragraph

Review in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Agatha Fischer-CarvalhoLaboratório de Ciclo Celular, Instituto Butantan, São Paulo 05503-900, SP, Brazil.ORCID 0009-0007-2481-2387
Tereza Cristina Taveira-BarbosaLaboratório de Ciclo Celular, Instituto Butantan, São Paulo 05503-900, SP, Brazil.
Sergio Verjovski-AlmeidaLaboratório de Ciclo Celular, Instituto Butantan, São Paulo 05503-900, SP, Brazil.ORCID 0000-0002-6356-2401
Simone HaeberleinBiomedizinisches Forschungszentrum Seltersberg, Institute of Parasitology, Justus Liebig University Giessen, Schubertstr. 81, 35392 Giessen, Germany.ORCID 0000-0002-1932-9696
Murilo Sena AmaralLaboratório de Ciclo Celular, Instituto Butantan, São Paulo 05503-900, SP, Brazil.ORCID 0000-0003-4999-5099

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 409278/2023-8Fundação de Amparo à Pesquisa do Estado de São Paulo 2018/23693-5LOEWE Centre DRUID LOEWE/1/10/519/03/03.001(0016)/53
6 · The paper itself

Abstract

Schistosomiasis is a neglected tropical disease that affects over 240 million people worldwide. Currently, praziquantel is the only drug recommended by the World Health Organization for treatment. However, cases of drug resistance have been reported, which indicates an urgent need for new therapeutics. In this context, natural compounds represent valuable sources of pharmacological substances. Plant-derived natural products have been greatly explored for their potential antischistosomal activity, while animal-derived compounds have received little attention. Recent advances in the biotechnology field allow the wide exploration of animal-derived compounds in drug discovery, which may represent a cost-effective option to find bioactive molecules also against

Indexed as

animal natural productsantiparasitic activityschistosomiasis

Identifiers

PMID40005763
PMCPMC11858059

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.