Evidence map›Paper›PMID 40005695›Full record

ReviewMicroorganisms2025

Antimicrobial Potential of Cannabinoids: A Scoping Review of the Past 5 Years.

Maria João Coelho, Maria Duarte Araújo, Márcia Carvalho, Inês Lopes Cardoso, Maria Conceição Manso, Cristina Pina

Abstract readReview
In one paragraph

Review in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Efficacy of Cannabidiol in Reducing Virulence ofInternational journal of molecular sciences · 2026
    Article
  6. Cannabidiol (CBD) InhibitsInternational journal of dentistry · 2026
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maria João CoelhoRISE-Health, Faculty of Health Sciences, Fernando Pessoa University, Fernando Pessoa Teaching and Culture Foundation, Rua Carlos da Maia, 296, 4200-150 Porto, Portugal.ORCID 0000-0002-9169-7776
Maria Duarte AraújoFCS-UFP, Faculdade de Ciências da Saúde (Health Sciences Faculty), Fernando Pessoa University, Rua Carlos da Maia, 296, 4200-150 Porto, Portugal.
Márcia CarvalhoRISE-Health, Faculty of Health Sciences, Fernando Pessoa University, Fernando Pessoa Teaching and Culture Foundation, Rua Carlos da Maia, 296, 4200-150 Porto, Portugal.ORCID 0000-0001-9884-4751
Inês Lopes CardosoRISE-Health, Faculty of Health Sciences, Fernando Pessoa University, Fernando Pessoa Teaching and Culture Foundation, Rua Carlos da Maia, 296, 4200-150 Porto, Portugal.ORCID 0000-0002-0693-9831
Maria Conceição MansoRISE-Health, Faculty of Health Sciences, Fernando Pessoa University, Fernando Pessoa Teaching and Culture Foundation, Rua Carlos da Maia, 296, 4200-150 Porto, Portugal.ORCID 0000-0002-1774-1337
Cristina PinaRISE-Health, Faculty of Health Sciences, Fernando Pessoa University, Fernando Pessoa Teaching and Culture Foundation, Rua Carlos da Maia, 296, 4200-150 Porto, Portugal.ORCID 0000-0001-8841-714X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the scenario of fighting bacterial resistance to antibiotics, natural products have been extensively investigated for their potential antibacterial activities. Among these, cannabinoids-bioactive compounds derived from cannabis-have garnered attention for their diverse biological activities, including anxiolytic, anti-inflammatory, analgesic, antioxidant, and neuroprotective properties. Emerging evidence suggests that cannabinoids may also possess significant antimicrobial properties, with potential applications in enhancing the efficacy of conventional antimicrobial agents. Therefore, this review examines evidence from the past five years on the antimicrobial properties of cannabinoids, focusing on underlying mechanisms such as microbial membrane disruption, immune response modulation, and interference with microbial virulence factors. In addition, their synergistic potential, when used alongside standard therapies, underscores their promise as a novel strategy to address drug resistance, although further research and clinical trials are needed to validate their therapeutic use. Overall, cannabinoids offer a promising avenue for the development of innovative treatments to combat drug-resistant infections and reduce the reliance on traditional antimicrobial agents.

Indexed as

antibacterialantifungalantimicrobial potentialantiviralcannabinoidscannabis

Identifiers

PMID40005695
PMCPMC11858408

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.