Evidence map›Paper›PMID 40005654›Full record

ArticleMicroorganisms2025

Natural Phenolics Disrupt Microbial Communication by Inhibiting Quorum Sensing.

Martin Helcman, Karel Šmejkal, Marie Čulenová, Tibor Béres, Jakub Treml

Abstract read
In one paragraph

Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
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  5. Article
  6. Review
  7. Review
  8. Protective Role ofMicroorganisms · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Martin HelcmanDepartment of Natural Drugs, Faculty of Pharmacy, Masaryk University, 612 00 Brno, Czech Republic.
Karel ŠmejkalDepartment of Natural Drugs, Faculty of Pharmacy, Masaryk University, 612 00 Brno, Czech Republic.ORCID 0000-0002-4336-7924
Marie ČulenováDepartment of Natural Drugs, Faculty of Pharmacy, Masaryk University, 612 00 Brno, Czech Republic.ORCID 0000-0002-1155-272X
Tibor BéresFaculty of Sciences, Palacký University, 779 00 Olomouc, Czech Republic.ORCID 0000-0002-5845-6903
Jakub TremlDepartment of Molecular Pharmacy, Faculty of Pharmacy, Masaryk University, 612 00 Brno, Czech Republic.ORCID 0000-0002-8690-9981

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Quorum sensing, a bacterial cell-to-cell communication mechanism, plays a key role in bacterial virulence and biofilm formation. Targeting quorum-sensing pathways represents a promising strategy for the development of novel antibacterial agents. This study evaluated the anti-quorum-sensing activities of 18 natural compounds, including cannabinoids, arylbenzofurans, flavonoids, caffeine, and chlorogenic acid, using the luminescent biosensor strain

Indexed as

antibacterialCannabis sativaMorus albaphenolicprenylquorum sensing

Identifiers

PMID40005654
PMCPMC11857621

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.