Evidence map›Paper›PMID 40005570›Full record

Observational studyPathogens (Basel, Switzerland)2025

Sex, Age, and Previous Herpes Zoster Infection Role on Adverse Events Following Immunization with Adjuvanted Recombinant Vaccine.

Maria Costantino, Valentina Giudice, Giuseppina Moccia, Monica Ragozzino, Salvatore Calabrese, Francesco Caiazzo, Massimo Beatrice, Walter Longanella, Simona Caruccio, Candida Iacuzzo and 7 more

Abstract readObservational Study
In one paragraph

Observational study in Pathogens (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Maria CostantinoDepartment of Medicine, Surgery, and Dentistry, University of Salerno, 84081 Baronissi, Italy.
Valentina GiudiceDepartment of Medicine, Surgery, and Dentistry, University of Salerno, 84081 Baronissi, Italy.ORCID 0000-0002-7492-6848
Giuseppina MocciaDepartment of Medicine, Surgery, and Dentistry, University of Salerno, 84081 Baronissi, Italy.ORCID 0000-0002-7017-7413
Monica RagozzinoUniversity Hospital "San Giovanni di Dio e Ruggi d'Aragona", 84131 Salerno, Italy.
Salvatore CalabreseUniversity Hospital "San Giovanni di Dio e Ruggi d'Aragona", 84131 Salerno, Italy.
Francesco CaiazzoUniversity Hospital "San Giovanni di Dio e Ruggi d'Aragona", 84131 Salerno, Italy.
Massimo BeatriceUniversity Hospital "San Giovanni di Dio e Ruggi d'Aragona", 84131 Salerno, Italy.
Walter LonganellaUniversity Hospital "San Giovanni di Dio e Ruggi d'Aragona", 84131 Salerno, Italy.
Simona CaruccioDepartment of Medicine, Surgery, and Dentistry, University of Salerno, 84081 Baronissi, Italy.
Candida IacuzzoUniversity Hospital "San Giovanni di Dio e Ruggi d'Aragona", 84131 Salerno, Italy.
Carmen GiuglianoUniversity Hospital "San Giovanni di Dio e Ruggi d'Aragona", 84131 Salerno, Italy.
Mariagrazia Bathilde MarongiuDepartment of Women, Child and General and Specialized Surgery, University "Luigi Vanvitelli", 80138 Naples, Italy.
Giovanni GenoveseUniversity Hospital "San Giovanni di Dio e Ruggi d'Aragona", 84131 Salerno, Italy.
Bianca SerioUniversity Hospital "San Giovanni di Dio e Ruggi d'Aragona", 84131 Salerno, Italy.
Emilia Anna VozzellaUniversity Hospital "San Giovanni di Dio e Ruggi d'Aragona", 84131 Salerno, Italy.
Amelia FilippelliDepartment of Medicine, Surgery, and Dentistry, University of Salerno, 84081 Baronissi, Italy.ORCID 0000-0002-8235-9118
Francesco De CaroDepartment of Medicine, Surgery, and Dentistry, University of Salerno, 84081 Baronissi, Italy.ORCID 0000-0001-9659-9940

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adverse events following immunizations (AEFIs) with recombinant zoster vaccine (RZV) are underexplored in fragile populations. This study aims to assess incidence, duration, and characteristics of AEFIs, focusing on the impact of sex, age, and prior Herpes Zoster (HZ) infection in a frail population, including solid organ transplant recipients. We conducted an observational study on patients receiving RZV, and AEFIs were classified as local or systemic and analyzed for incidence, duration, and patterns across groups. We showed that females had a higher incidence of AEFIs (

Indexed as

Drug-Related Side Effects and Adverse ReactionsHerpes ZosterHerpes Zoster VaccineAdultAgedAged, 80 and overAge FactorsFemaleHumansIncidenceMaleMiddle AgedSex FactorsVaccinationVaccines, SyntheticHerpes Zoster VaccineVaccines, SyntheticAEFIage-related responsesfragile populationsgender differencerecombinant zoster vaccine (RZV)

Identifiers

PMID40005570
PMCPMC11858321

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.