Evidence map›Paper›PMID 40005487›Full record

ArticlePathogens (Basel, Switzerland)2025

A One Health Zoonotic Vector Borne Infectious Disease Family Outbreak Investigation.

Edward B Breitschwerdt, Ricardo G Maggi, Charlotte O Moore, Cynthia Robveille, Rosalie Greenberg, Emily Kingston

Abstract readCase Reports
In one paragraph

Article in Pathogens (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Molecular Detection ofPathogens (Basel, Switzerland) · 2026
    Article
  5. Infectious diseases and childhood disruptive behavior disorders: a reappraisal.Frontiers in cellular and infection microbiology · 2026
    Article
  6. Pathogens (Basel, Switzerland) · 2025
    Article
  7. Prevalence and clinical profiles ofJournal of advanced veterinary and animal research · 2025
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Edward B BreitschwerdtIntracellular Pathogens Research Laboratory, Comparative Medicine Institute, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27607, USA.ORCID 0000-0002-3506-0279
Ricardo G MaggiIntracellular Pathogens Research Laboratory, Comparative Medicine Institute, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27607, USA.ORCID 0000-0001-7428-0138
Charlotte O MooreIntracellular Pathogens Research Laboratory, Comparative Medicine Institute, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27607, USA.ORCID 0000-0002-1173-6019
Cynthia RobveilleIntracellular Pathogens Research Laboratory, Comparative Medicine Institute, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27607, USA.ORCID 0000-0002-2264-307X
Rosalie GreenbergMedical Arts Psychotherapy Associates, P.A., 33 Overlook Road, Suite 406, Summit, NJ 07907, USA.
Emily KingstonIntracellular Pathogens Research Laboratory, Comparative Medicine Institute, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27607, USA.ORCID 0009-0004-7871-7519

Funding

Steven & Alexandra Cohen Foundation Lyme74
6 · The paper itself

Abstract

This study reinforces the value of a One Health approach to infectious disease outbreak investigations. After the onset of neuropsychiatric symptoms in their son, our investigation focused on a family composed of a mother, father, two daughters, the son, two dogs, and a rabbit, all with exposures to vectors (fleas and ticks), rescued dogs, and other animals. Between 2020 and 2022, all family members experienced illnesses that included neurological symptoms. Prolonged menorrhagia (130d) in the youngest daughter ultimately resolved following antibiotic administration. One dog was diagnosed with a splenic hematoma and months later spinal histiocytic sarcoma. The father, both daughters, and one dog were seroreactive to multiple

Indexed as

Disease OutbreaksOne HealthVector Borne DiseasesZoonosesAdultAnimalsBabesiaBartonella InfectionsDisease VectorsDog DiseasesDogsFemaleHumansMaleRabbitsBabesiaBartonelladigital PCRfleainfectionneuropsychiatrictickvector

Identifiers

PMID40005487
PMCPMC11858541

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.