Evidence map›Paper›PMID 40005458›Full record

ReviewMedicina (Kaunas, Lithuania)2025

Sarcoidosis-Associated Pulmonary Hypertension.

Yoshitaka Morimatsu, Nobuhiro Tahara, Masaki Okamoto, Munehisa Bekki, Atsuko Tahara, Yoshiko Eto, Tadahiro Kugai, Yuki Koga, Shoko Maeda-Ogata, Akihiro Honda and 6 more

Abstract readReview
In one paragraph

Review in Medicina (Kaunas, Lithuania), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Yoshitaka MorimatsuDepartment of Environmental Medicine, Kurume University School of Medicine, Kurume 830-0011, Japan.
Nobuhiro TaharaDivision of Cardiovascular Medicine, Department of Medicine, Kurume University School of Medicine, Kurume 830-0011, Japan.ORCID 0000-0003-2011-8201
Masaki OkamotoDepartment of Respirology, NHO Kyushu Medical Center, Fukuoka 810-0065, Japan.ORCID 0000-0002-9298-3504
Munehisa BekkiDivision of Cardiovascular Medicine, Department of Medicine, Kurume University School of Medicine, Kurume 830-0011, Japan.
Atsuko TaharaDivision of Cardiovascular Medicine, Department of Medicine, Kurume University School of Medicine, Kurume 830-0011, Japan.
Yoshiko EtoDivision of Cardiovascular Medicine, Department of Medicine, Kurume University School of Medicine, Kurume 830-0011, Japan.
Tadahiro KugaiDivision of Cardiovascular Medicine, Department of Medicine, Kurume University School of Medicine, Kurume 830-0011, Japan.
Yuki KogaDivision of Cardiovascular Medicine, Department of Medicine, Kurume University School of Medicine, Kurume 830-0011, Japan.
Shoko Maeda-OgataDivision of Cardiovascular Medicine, Department of Medicine, Kurume University School of Medicine, Kurume 830-0011, Japan.
Akihiro HondaDivision of Cardiovascular Medicine, Department of Medicine, Kurume University School of Medicine, Kurume 830-0011, Japan.
Sachiyo IgataDivision of Cardiovascular Medicine, Department of Medicine, Kurume University School of Medicine, Kurume 830-0011, Japan.
Yoshiaki ZaizenDivision of Respirology, Neurology and Rheumatology, Department of Internal Medicine, Kurume University School of Medicine, Kurume 830-0011, Japan.ORCID 0000-0003-2274-4599
Shuichi TanoueDepartment of Radiology, Kurume University School of Medicine, Kurume 830-0011, Japan.
Tomoaki HoshinoDivision of Respirology, Neurology and Rheumatology, Department of Internal Medicine, Kurume University School of Medicine, Kurume 830-0011, Japan.
Tatsuya IshitakeDepartment of Environmental Medicine, Kurume University School of Medicine, Kurume 830-0011, Japan.
Yoshihiro FukumotoDivision of Cardiovascular Medicine, Department of Medicine, Kurume University School of Medicine, Kurume 830-0011, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sarcoidosis is a granulomatous disorder of unknown etiology characterized by multisystem non-caseating granulomas. Pulmonary hypertension (PH) is a well-known complication of sarcoidosis and is associated with increased morbidity and mortality. The actual epidemiology of sarcoidosis-associated PH (SAPH) remains unknown, and its pathogenesis has not been fully elucidated. SAPH is classified under the miscellaneous category (group 5 of the PH classification). The clinical presentation of SAPH is variable and not always proportional to the severity of sarcoidosis. Appropriate management for SAPH by an experienced physician is important; however, no treatment algorithm for SAPH has been established. Lung transplantation should be considered in refractory cases. Pulmonary arterial hypertension-specific vasodilators targeting the endothelin pathway, nitric oxide pathway, and prostacyclin pathway have improved the clinical functions and hemodynamics in some patients with SAPH.

Indexed as

Hypertension, PulmonarySarcoidosisHumansVasodilator AgentsVasodilator Agentsepidemiologypathogenesissarcoidosissarcoidosis-associated pulmonary hypertensiontreatment

Identifiers

PMID40005458
PMCPMC11857724

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.