Evidence map›Paper›PMID 40005455›Full record

ArticleMedicina (Kaunas, Lithuania)2025

Cutaneous Anguillulosis During Immunotherapy for Metastatic Renal Cell Carcinoma.

Pierre Cornillon, Marie Beguinot, Denis Maillet, Wafa Bouleftour, Yanis Bouqallaba, Pierre Flori, Pauline Corbaux, Guorong Li

Abstract readCase Reports
In one paragraph

Article in Medicina (Kaunas, Lithuania), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Pierre CornillonDepartment of Medical Oncology, North Hospital, CHU Saint Etienne, 42000 Saint Etienne, France.
Marie BeguinotDepartment of Medical Oncology, Medipole Lyon Villeurbanne Mutualist Clinic, 69100 Lyon, France.
Denis MailletDepartment of Medical Oncology, IMMUCARE, Centre Hospitalier Lyon Sud, Institut de Cancérologie des Hospices de Lyon, 69152 Pierre-Bénite, France.
Wafa BouleftourDepartment of Medical Oncology, North Hospital, CHU Saint Etienne, 42000 Saint Etienne, France.ORCID 0000-0002-8485-9386
Yanis BouqallabaDepartment of Medical Oncology, North Hospital, CHU Saint Etienne, 42000 Saint Etienne, France.
Pierre FloriLaboratory of Parasitology, North Hospital, CHU Saint Etienne, 42000 Saint Etienne, France.
Pauline CorbauxDepartment of Medical Oncology, North Hospital, CHU Saint Etienne, 42000 Saint Etienne, France.ORCID 0000-0001-8832-2562
Guorong LiDepartment of Urology, North Hospital, CHU Saint Etienne, 42000 Saint Etienne, France.ORCID 0000-0003-4457-3380

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunotherapy has been widely applied to treat metastatic renal cell cancer patients. Managing the side effects of immunotherapy can be a challenge. Here, we describe a rare presentation of cutaneous anguillulosis during immunotherapy. The patient experienced a rash eruption after receiving immunotherapy for metastatic renal cell cancer. The diagnosis of skin toxicity caused by immunotherapy was rejected after the failure of treatment by cortisone. The travelling history and a laboratory test confirmed the presence of anguillulosis infection. A diagnosis of cutaneous anguillulosis was established. Satisfactory treatment with ivermectin was achieved for cutaneous lesions. Immunotherapy was restored without any skin symptoms. We suggested the possible mechanism of cutaneous demonstration of immune inflammatory syndrome during the immunotherapy of a cancer patient with parasitic infection. It was concluded that a comprehensive search for previous infectious pathogens should be performed to ensure a correct diagnosis and timely treatment.

Indexed as

Carcinoma, Renal CellImmunotherapyKidney NeoplasmsHumansIvermectinMaleMiddle AgedIvermectincutaneous anguillulosisimmunotherapyIRISmetastatic renal cell carcinomaskin toxicity

Identifiers

PMID40005455
PMCPMC11857144

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.