Evidence map›Paper›PMID 40005254›Full record

ArticleMolecules (Basel, Switzerland)2025

Evaluation of Antibacterial and Antibiofilm Properties of Phenolics with Coumarin, Naphthoquinone and Pyranone Moieties Against Foodborne Microorganisms.

Alejandra Alejo-Armijo, Antonio Cobo, Alfonso Alejo-Armijo, Joaquín Altarejos, Sofía Salido, Elena Ortega-Morente

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Natural Product-Based Therapeutic Potential ofPharmaceuticals (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Bioactive Compounds and Traditional Uses ofMolecules (Basel, Switzerland) · 2025
    Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alejandra Alejo-ArmijoDepartment of Health Sciences, Faculty of Experimental Sciences, University of Jaén, Campus of International Excellence in Agri-Food (ceiA3), 23071 Jaén, Spain.
Antonio CoboDepartment of Health Sciences, Faculty of Experimental Sciences, University of Jaén, Campus of International Excellence in Agri-Food (ceiA3), 23071 Jaén, Spain.ORCID 0000-0003-3360-7186
Alfonso Alejo-ArmijoDepartment of Inorganic and Organic Chemistry, Faculty of Experimental Sciences, University of Jaén, Campus of International Excellence in Agri-Food (ceiA3), 23071 Jaén, Spain.ORCID 0000-0001-8691-4628
Joaquín AltarejosDepartment of Inorganic and Organic Chemistry, Faculty of Experimental Sciences, University of Jaén, Campus of International Excellence in Agri-Food (ceiA3), 23071 Jaén, Spain.ORCID 0000-0002-5532-8535
Sofía SalidoDepartment of Inorganic and Organic Chemistry, Faculty of Experimental Sciences, University of Jaén, Campus of International Excellence in Agri-Food (ceiA3), 23071 Jaén, Spain.ORCID 0000-0003-2319-7873
Elena Ortega-MorenteDepartment of Health Sciences, Faculty of Experimental Sciences, University of Jaén, Campus of International Excellence in Agri-Food (ceiA3), 23071 Jaén, Spain.ORCID 0000-0001-6281-5000

Funding

Andalusian Consejería de Economía y Conocimiento (FEDER program 2014-2020). Spain 1380669
6 · The paper itself

Abstract

Numerous studies have previously demonstrated the antimicrobial activity of plant extracts rich in procyanidins. However, these investigations that focused on uncharacterized extracts do not provide information on the structure-activity relationships of these compounds. The aim of this work was to investigate the antibacterial and antibiofilm properties of 27 phenolics with coumarin, naphthoquinone and pyranone moieties against foodborne microorganisms, as well as to establish structure-activity relationships. Minimal inhibitory concentrations (MICs) for each compound were investigated, as well as their ability for inhibiting biofilm formation as well as disrupting previously formed biofilms by food pathogens. Our compounds show high antibacterial and antibiofilm activities against Gram-positive bacteria. Regarding the structure-activity relationships observed, the coumarin moiety seems to favor the antibacterial activity against both

Indexed as

Anti-Bacterial AgentsBiofilmsCoumarinsNaphthoquinonesPhenolsFood MicrobiologyGram-Positive BacteriaMicrobial Sensitivity TestsStructure-Activity RelationshipAnti-Bacterial AgentscoumarinCoumarinsNaphthoquinonesPhenolsantibacterial activityantibiofilm activitycoumarinfoodborne bacterianaphthoquinoneprocyanidin analogs

Identifiers

PMID40005254
PMCPMC11857956

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.