ReviewMolecules (Basel, Switzerland)2025
Large Scale Synthesis of Carbon Dots and Their Applications: A Review.
Review in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Targeting the HIF-1α/PPARγ axis with curcumin carbon dots to combat uranium nephrotoxicity.Journal of nanobiotechnology · 2026Article
- A critical review on antibacterial mechanisms of carbon dots: a comprehensive approach to combating multidrug resistance.Archives of microbiology · 2026Review
- Carbon Dots in Nanomedicine: Advanced Fabrication, Biomedical Applications, and Future Clinical Perspectives.Pharmaceutics · 2026Review
- A Review on Agro-Waste-Derived Carbon Dots as Multifunctional Nanofillers in Biopolymer Films: A Sustainable Strategy for Active Packaging and Shelf Life Extension of Seafood.Foods (Basel, Switzerland) · 2026Review
- Antipathogenic carbon dots synthesized from fluorescent amino acids and their photodynamic activity.Discover nano · 2026Article
- Transformational Catalytic Innovation Supports COChemistryOpen · 2026Review
- Carbon Dot-Based Electrochemical and Optical Sensors for Pharmaceutical Analysis and Point-of-Care Diagnostics.Biosensors · 2026Review
- Fluorescent Poly(vinyl alcohol) Composite Films Incorporating Doped Carbon Dots for Heavy Metal Detection in Smart Packaging Applications.ACS omega · 2026Article
- Enhanced biosensing of diabetes biomarkers by using rationally engineered carbon dots.RSC advances · 2026Review
- Carbon dot-integrated edible films: emerging synergies for advanced food packaging applications.RSC advances · 2026Review
- Recent Progress on Carbon-Dots-Based Probes for Microbial Labeling and Versatile Analysis Applications.Biosensors · 2026Review
- Carbon Dots and Mitochondria-Advances in Targeting, Imaging, and Therapeutics.International journal of molecular sciences · 2026Review
- Next-Generation Carbon-Based Quantum Dots for Healthcare and Beauty Applications.Nanomaterials (Basel, Switzerland) · 2026Review
- Sustainable Carbon Nanomaterials from Biomass Precursors: Green Synthesis Strategies and Environmental Applications.Nanomaterials (Basel, Switzerland) · 2026Review
- Carbon Quantum Dots as Versatile Nanosystems for Biomedical Innovation: Mechanisms, Applications, and Translational Prospects.British journal of biomedical science · 2026Review
- Highly selective sensing of tetracycline by fluorescent carbon dots derived from spent coffee groundsRSC advances · 2025Article
- Recent progress in biowaste-derived carbon dots for cancer theranostics toward a green solution to toxic metal quantum dots.Discover nano · 2025Review
- Reproducibility roadblocks and standardization in carbon dot synthesis: a critical review of current practices, challenges, and future directions.Mikrochimica acta · 2025Review
- A Review on Emerging Technologies in Pharmaceutical Packaging: From Anti-Counterfeiting to Green Solutions.AAPS PharmSciTech · 2025Review
- Sustainable Carbon Dots from Cellulose Precursors for Environmental Sensing: Recent Trends and Outlook.Nanomaterials (Basel, Switzerland) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Carbon dots (CDs), a versatile class of fluorescent carbon-based nanomaterials, have attracted widespread attention due to their exceptional optical properties, biocompatibility, and cost-effectiveness. Their applications span biomedicine, optoelectronics, and smart food packaging, yet large-scale synthesis remains a significant challenge. This review categorizes large-scale synthesis methods into liquid-phase (hydrothermal/solvothermal, microwave-assisted, magnetic hyperthermia, aldol condensation polymerization), gas-phase (plasma synthesis), solid-phase (pyrolysis, oxidation/carbonization, ball milling), and emerging techniques (microfluidic, ultrasonic, molten-salt). Notably, microwave-assisted and solid-state synthesis methods show promise for industrial production due to their scalability and efficiency. Despite these advances, challenges persist in optimizing synthesis reproducibility, reducing energy consumption, and developing purification methods and quality control strategies. Addressing these issues will be critical for transitioning CDs from laboratory research to real-world applications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.