Evidence map›Paper›PMID 40005082›Full record

ArticleMolecules (Basel, Switzerland)2025

Identification and Therapeutic Potential of Polymethoxylated Flavones in

Xinyu Wang, Zirong Yi, Yiming Zhang, Jing Zhang, Xueyan Li, Dongying Qi, Qianqian Wang, Xiaoyu Chai, Huan Liu, Guopeng Wang and 3 more

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Xinyu WangSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.
Zirong YiSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.
Yiming ZhangInstitute of Information on Traditional Chinese Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Jing ZhangInstitute of Information on Traditional Chinese Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Xueyan LiSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.ORCID 0000-0001-5134-1321
Dongying QiSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.
Qianqian WangSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.
Xiaoyu ChaiSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.
Huan LiuSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.
Guopeng WangZhongcai Health (Beijing) Biological Technology Development Co., Ltd., Beijing 101500, China.
Yanli PanInstitute of Information on Traditional Chinese Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Yang LiuSchool of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 102488, China.ORCID 0000-0003-3439-010X
Guohua YuSchool of Life Sciences, Beijing University of Chinese Medicine, Beijing 102488, China.ORCID 0000-0002-1267-3507

Funding

China Academy of Chinese Medical Sciences (CACMS) Innovation Fund CI2021A00511
6 · The paper itself

Abstract

Neuroinflammation is a significant driving force in the pathogenesis and progression of central nervous system (CNS) disorders. Polymethoxylated flavones (PMFs), the key lipid-soluble constituents in

Indexed as

Alzheimer DiseaseCitrusFlavonesNeuroinflammatory DiseasesPlant ExtractsAnimalsAnti-Inflammatory AgentsBlood-Brain BarrierDisease Models, AnimalMaleMiceNeuroprotective AgentsAnti-Inflammatory AgentsFlavonesNeuroprotective AgentsnobiletinPlant ExtractsAlzheimer’s diseaseanti-neuroinflammationCitri Reticulatae Pericarpiumnetwork pharmacologypolymethoxylated flavonessequential metabolism method

Identifiers

PMID40005082
PMCPMC11857992

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.