ArticleNutrients2025
Gut Microbiota Profile and Functional Gastrointestinal Disorders in Infants: A Longitudinal Study.
Article in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Gastrointestinal microbiota alterations associated with pediatric gastroesophageal reflux disease and proton pump inhibitor exposure: a systematic review of microbiome changes, dysbiosis markers, and associated clinical outcomes.Frontiers in nutrition · 2026Pooled it
- Infant gut microbiota following cesarean section in the Middle East: a multidisciplinary expert consensus based on a targeted narrative review.Frontiers in pediatrics · 2026Pooled it
- Lactiplantibacillus plantarum Z6 Improves Functional Constipation in Infants.Biotechnology journal · 2026Trial
- Efficacy ofFrontiers in nutrition · 2026Trial
- Gastrointestinal consequences of cesarean section birth: A systematic review of short- and long-term effects in infancy and beyond.World journal of clinical pediatrics · 2026Article
- [Prevalence and Influencing Factors of Functional Gastrointestinal Disorders Among Infants Aged 0 to 9 Months With Gastrointestinal Discomfort in China: A Multicenter Cross-Sectional Survey].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2025Article
- Infantile Colic: When to Suspect Cow's Milk Allergy.Nutrients · 2025Review
- The role of intestinal gases in pediatric functional constipation: a narrative review of pathophysiology and emerging therapeutics.Frontiers in nutrition · 2025Review
- Functional constipation in Chinese infants: disruptions in gut microbiota and urinary metabolome revealed by a cross-sectional analysis.Frontiers in microbiology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
objectivesThe gut microbiota is involved in modulating gastrointestinal function and consequently contributes to the manifestation of functional gastrointestinal disorders (FGIDs). The aim of the study was to analyze the composition of the gut microbiota in infants with functional gastrointestinal disorders (infantile colic, functional constipation, gastroesophageal reflux, functional diarrhea) according to age, environmental factors, and clinical manifestations.
methodsThe study involved the clinical and laboratory examination of 134 infants divided into two groups: group I (
resultsInfants with functional gastrointestinal disorders presented an imbalance of intestinal microflora, which was characterized by a significant decrease in the main representatives of acidifying flora represented by
conclusionsThe imbalance of acidifying and proteolytic microbial composition in the gut could be the key to the occurrence of functional gastrointestinal disorders in the first year of life.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.