Evidence map›Paper›PMID 40005008›Full record

ArticleNutrients2025

Association of Oxidative Stress Markers with Incident Hyperglycemia in Gestational Diabetes Mellitus in an Educational Intervention.

Mónica L Ruiz-Martínez, Rita A Gómez-Díaz, Adriana Leticia Valdez González, Selene Ángeles Mejía, Rafael Mondragón González, Margarita Díaz Flores, Ricardo César Saldaña Espinoza, Luz Angélica Ramírez-García, Mary Flor Díaz Velázquez, Niels H Wacher

Abstract read
In one paragraph

Article in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mónica L Ruiz-MartínezUnidad de Investigación Médica en Epidemiología Clínica UMAE HE CMN SXXI, Instituto Mexicano del Seguro Social (IMSS), Av. Cuauhtemoc 330, Mexico City 06720, Mexico.ORCID 0000-0001-8228-8228
Rita A Gómez-DíazUnidad de Investigación Médica en Epidemiología Clínica UMAE HE CMN SXXI, Instituto Mexicano del Seguro Social (IMSS), Av. Cuauhtemoc 330, Mexico City 06720, Mexico.ORCID 0000-0002-2191-4931
Adriana Leticia Valdez GonzálezUnidad de Investigación Médica en Epidemiología Clínica UMAE HE CMN SXXI, Instituto Mexicano del Seguro Social (IMSS), Av. Cuauhtemoc 330, Mexico City 06720, Mexico.
Selene Ángeles MejíaUnidad de Investigación Médica en Epidemiología Clínica UMAE HE CMN SXXI, Instituto Mexicano del Seguro Social (IMSS), Av. Cuauhtemoc 330, Mexico City 06720, Mexico.
Rafael Mondragón GonzálezUnidad de Investigación Médica en Epidemiología Clínica UMAE HE CMN SXXI, Instituto Mexicano del Seguro Social (IMSS), Av. Cuauhtemoc 330, Mexico City 06720, Mexico.ORCID 0000-0002-5673-3540
Margarita Díaz FloresUnidad de Investigación Médica en Epidemiología Clínica UMAE HE CMN SXXI, Instituto Mexicano del Seguro Social (IMSS), Av. Cuauhtemoc 330, Mexico City 06720, Mexico.
Ricardo César Saldaña EspinozaUnidad de Investigación Médica en Epidemiología Clínica UMAE HE CMN SXXI, Instituto Mexicano del Seguro Social (IMSS), Av. Cuauhtemoc 330, Mexico City 06720, Mexico.ORCID 0000-0002-2200-7743
Luz Angélica Ramírez-GarcíaServicio de Endocrinología, Unidad Médica de Alta Especialidad, Hospital de Gineco-Obstetricia No. 4 "Luis Castelazo Ayala", Instituto Mexicano del Seguro Social (IMSS), Rio de la Magdalena 289, Mexico City 01090, Mexico.
Mary Flor Díaz VelázquezUnidad Médica de Alta Especialidad, Hospital de Gineco-Obstetricia No. 3, Centro Médico Nacional "La Raza", Dr. Víctor Manuel Espinosa de los Reyes Sánchez, Instituto Mexicano del Seguro Social (IMSS), Eje vial 1 Poniente, Mexico City 02990, Mexico.
Niels H WacherUnidad de Investigación Médica en Epidemiología Clínica UMAE HE CMN SXXI, Instituto Mexicano del Seguro Social (IMSS), Av. Cuauhtemoc 330, Mexico City 06720, Mexico.ORCID 0000-0002-7717-6704

Funding

Coordinacion de Investigacion en Salud FIS-2023-3-117Coordinación de Investigación en Salud FIS/IMSS/PROT/ESP/1851Fundacion Gonzalo Rio Arronte S.0634
6 · The paper itself

Abstract

BACKGROUND/

objectiveThis study is aimed to assess the link between oxidative stress markers and incident hyperglycemia in women with gestational diabetes mellitus (GDM) during an educational intervention.

methodsThe study used a prospective cohort. Pregnant women with GDM who were 18-40 years old (

resultsA total of 6% progressed to T2D, and 36.8% to prediabetes. At baseline, Ihypergly women exhibited elevated oxidative stress markers and adiponectin, and lower antioxidant capacity. Post-intervention, they showed higher antioxidant capacity, GSH, and adiponectin, and lower MDA. Basal malondialdehyde, pregestational BMI, HbA1c, and sugary food consumption positively correlated with Ihypergly. A high intake of antioxidants inversely correlated with incident hyperglycemia.

conclusionsHigher concentrations of plasma markers of oxidative stress are associated with postpartum incident hyperglycemia in women with gestational diabetes.

Indexed as

Diabetes, GestationalHyperglycemiaOxidative StressAdiponectinAdolescentAdultBiomarkersBlood GlucoseDiabetes Mellitus, Type 2FemaleGlucose Tolerance TestHumansIncidencePregnancyProspective StudiesYoung AdultAdiponectinBiomarkersBlood Glucosegestational diabetes mellitusincident hyperglycemiaoxidative stress markers

Identifiers

PMID40005008
PMCPMC11858598

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.