Evidence map›Paper›PMID 40005006›Full record

SynthesisNutrients2025

Maternal Phenylketonuria and Offspring Outcome: A Retrospective Study with a Systematic Review of the Literature.

Guido Leone, Concetta Meli, Raffaele Falsaperla, Federica Gullo, Laura Licciardello, Luisa La Spina, Marianna Messina, Manuela Lo Bianco, Annamaria Sapuppo, Maria Grazia Pappalardo and 6 more

Abstract readSystematic Review
In one paragraph

Synthesis in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Guido LeonePostgraduate Training Program in Pediatrics, University of Catania, 95125 Catania, Italy.
Concetta MeliUnit of Expanded Neonatal Screening and Inherited Metabolic Diseases, Pediatric Clinic, Department of Medical Sciences, University of Catania, 95123 Catania, Italy.
Raffaele FalsaperlaUnit of Pediatrics, University of Ferrara, 44121 Ferrara, Italy.
Federica GulloPostgraduate Training Program in Pediatrics, University of Catania, 95125 Catania, Italy.
Laura LicciardelloPostgraduate Training Program in Pediatrics, University of Catania, 95125 Catania, Italy.
Luisa La SpinaUnit of Expanded Neonatal Screening and Inherited Metabolic Diseases, Pediatric Clinic, Department of Medical Sciences, University of Catania, 95123 Catania, Italy.ORCID 0000-0003-1218-6407
Marianna MessinaUnit of Expanded Neonatal Screening and Inherited Metabolic Diseases, Pediatric Clinic, Department of Medical Sciences, University of Catania, 95123 Catania, Italy.ORCID 0000-0002-8652-4248
Manuela Lo BiancoUnit of Pediatric Clinic, Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.
Annamaria SapuppoUnit of Pediatrics and Pediatric Emergency, AOU "Policlinico" PO "San Marco", 95123 Catania, Italy.ORCID 0000-0001-9433-026X
Maria Grazia PappalardoUnit of Expanded Neonatal Screening and Inherited Metabolic Diseases, Pediatric Clinic, Department of Medical Sciences, University of Catania, 95123 Catania, Italy.
Riccardo IacobacciUnit of Expanded Neonatal Screening and Inherited Metabolic Diseases, Pediatric Clinic, Department of Medical Sciences, University of Catania, 95123 Catania, Italy.
Alessia ArenaUnit of Expanded Neonatal Screening and Inherited Metabolic Diseases, Pediatric Clinic, Department of Medical Sciences, University of Catania, 95123 Catania, Italy.ORCID 0000-0003-3049-9247
Michele VecchioRehabilitation Unit, Department of Biomedical and Biotechnological Sciences, University of Catania, 95123 Catania, Italy.
Martino RuggieriUnit of Pediatric Clinic, Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.
Agata PolizziUnit of Pediatric Clinic, Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.
Andrea Domenico PraticòUnit of Pediatrics, Department of Medicine and Surgery, University Kore of Enna, 94100 Enna, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Phenylketonuria, MaternalPregnancy OutcomeAdultFemaleHumansInfant, NewbornPhenylalaninePregnancyRetrospective StudiesPhenylalaninedietmaternal therapyoutcomephenylalaninephenylketonuria

Identifiers

PMID40005006
PMCPMC11858056

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.