Evidence map›Paper›PMID 40005002›Full record

Trial reportNutrients2025

A Randomized Phase II/III Trial Evaluating the Efficacy and Safety of 100 and 125 µg of Calcifediol Weekly Treatment of Severe Vitamin D Deficiency.

Jose Luis Pérez-Castrillón, Esteban Jódar-Gimeno, Ján Nociar, Michal Lojka, Dimitar Nikolov, Fernando Cereto-Castro, Snežana Novković, Umberto Tarantino, Nadia Mehsen-Cetre, Paula Arranz and 3 more

Abstract readRandomized Controlled TrialClinical Trial, Phase IIMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jose Luis Pérez-CastrillónDepartment of Internal Medicine, Río Hortega University Hospital, 47012 Valladolid, Spain.ORCID 0000-0002-1723-217X
Esteban Jódar-GimenoDepartment of Endocrinology and Nutrition, Quirón Madrid University Hospital, Universidad Europea, 28670 Madrid, Spain.ORCID 0000-0002-1234-8560
Ján NociarDepartment of Cardiology, General Hospital with Polyclinic Lučenec n.o., 98401 Lučenec, Slovakia.
Michal LojkaOrdinace MediFem, s.r.o., 41501 Teplice, Czech Republic.ORCID 0009-0006-3206-7834
Dimitar NikolovDepartment of Rheumatology, Medical Center-1-Sevlievo, 5400 Sevlievo, Bulgaria.
Fernando Cereto-CastroDepartment of Internal Medicine, Hospital Quirón Barcelona, 08023 Barcelona, Spain.
Snežana NovkovićDepartment of Internal Medicine, Institute of Rheumatology, 11000 Belgrade, Serbia.
Umberto TarantinoDepartment of Orthopaedics and Traumatology, Policlinico Tor Vergata Foundation, 00133 Rome, Italy.ORCID 0000-0003-0330-2189
Nadia Mehsen-CetreService de Rhumatologie CHU Pellegrin-Tripode, 33000 Bordeaux, France.
Paula ArranzClinical Research Department, FAES FARMA, 48940 Leioa, Spain.
Cristina Martínez OstaléClinical Research Department, FAES FARMA, 48940 Leioa, Spain.
Aintzane García-BeaMedical Affairs Department, FAES FARMA, 48940 Leioa, Spain.
Inmaculada GilaberteClinical Research Department, FAES FARMA, 48940 Leioa, Spain.

Funding

Faes Farma (Spain) 2020-001099-14
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CalcifediolVitamin D DeficiencyAdultAgedDouble-Blind MethodDrug Administration ScheduleFemaleHumansMaleMiddle AgedTreatment OutcomeVitamin DCalcifediolVitamin Dcalcifediolefficacysafetyvitamin D deficiencyweekly treatment

Identifiers

PMID40005002
PMCPMC11857939

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.