Evidence map›Paper›PMID 40004761›Full record

ReviewJournal of clinical medicine2025

Diagnostic Challenges in the Management of Aortic Valve Stenosis and the Role of Imaging: A Narrative Review.

Dimitrios Karelas, Evangelos Tatsis, Dimitrios Oikonomidis, Constantinos Hristou Papadopoulos

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dimitrios Karelas2nd Cardiology Department, "Korgialenio-Benakio" Red Cross Hospital, 11526 Athens, Greece.ORCID 0000-0002-2924-8793
Evangelos Tatsis2nd Cardiology Department, "Korgialenio-Benakio" Red Cross Hospital, 11526 Athens, Greece.ORCID 0009-0000-9356-5702
Dimitrios Oikonomidis2nd Cardiology Department, "Korgialenio-Benakio" Red Cross Hospital, 11526 Athens, Greece.ORCID 0000-0003-0697-6656
Constantinos Hristou Papadopoulos2nd Cardiology Department, "Korgialenio-Benakio" Red Cross Hospital, 11526 Athens, Greece.ORCID 0000-0002-2566-7173

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aortic valve stenosis (AS) is a prevalent and progressive valvular disease that poses significant diagnostic challenges, particularly in low-flow, low-gradient (LF-LG) states. Accurate assessment of AS severity is crucial for timely intervention and improved clinical outcomes. This narrative review critically evaluates the limitations of conventional echocardiographic techniques and explores the role of multimodal imaging-including advanced echocardiography, computed tomography (CT), and cardiac magnetic resonance (CMR)-in enhancing diagnostic accuracy. Special emphasis is placed on the unique challenges of LF-LG AS, where standard Doppler-derived assessments may misclassify disease severity, necessitating a more integrative diagnostic approach. By addressing these key diagnostic uncertainties and proposing a multimodal framework for improved assessment, this review provides a comprehensive update on best practices in AS evaluation, with the goal of optimizing clinical decision making and patient outcomes.

Indexed as

aortic valve stenosisechocardiographyimaginglow-flow, low-gradient aortic stenosis

Identifiers

PMID40004761
PMCPMC11856245

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.