Evidence map›Paper›PMID 40004732›Full record

ReviewJournal of clinical medicine2025

Real-World Effectiveness, Safety, and Tolerability of Facilitated Subcutaneous Immunoglobulin 10% in Secondary Immunodeficiency Disease: A Systematic Literature Review.

Maria Dimou, Angelo Vacca, Silvia Sánchez-Ramón, Ewa Karakulska-Prystupiuk, Vikte Lionikaite, Csaba Siffel, Colin Anderson-Smits, Marta Kamieniak

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Maria DimouDepartment of Hematology and Bone Marrow Transplantation Unit, National and Kapodistrian University of Athens, 15772 Athens, Greece.ORCID 0000-0001-8197-9895
Angelo VaccaUnit of Internal Medicine "Guido Baccelli", Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari Aldo Moro, Piazza Giulio Cesare, 11, I-70124 Bari, Italy.ORCID 0000-0002-4567-8216
Silvia Sánchez-RamónHospital Clínico San Carlos, Complutense University of Madrid, E-28040 Madrid, Spain.ORCID 0000-0001-9585-6167
Ewa Karakulska-PrystupiukDepartment of Hematology, Transplantation and Internal Medicine, Medical University of Warsaw, 02-091 Warsaw, Poland.ORCID 0000-0002-0201-5041
Vikte LionikaiteOxford PharmaGenesis, Oxford OX13 5QJ, UK.
Csaba SiffelTakeda Development Center Americas, Inc., Cambridge, MA 02142, USA.ORCID 0000-0002-6491-6953
Colin Anderson-SmitsTakeda Development Center Americas, Inc., Cambridge, MA 02142, USA.
Marta KamieniakTakeda Development Center Americas, Inc., Cambridge, MA 02142, USA.

Funding

Takeda Pharmaceuticals International AG N/A
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

hyaluronidase-facilitated subcutaneous immunoglobulin (fSCIG) 10%infectionreal-world evidencesafetysecondary immunodeficiencytolerability

Identifiers

PMID40004732
PMCPMC11856383

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.