Evidence map›Paper›PMID 40004618›Full record

ArticleJournal of clinical medicine2025

Effectiveness of Brodalumab for the Treatment of Moderate-to-Severe Psoriasis: A Retrospective, Real-World Multicenter Study with a Focus on Obese and Multi-Failure Patients-IL PSO (Italian Landscape Psoriasis).

Diego Orsini, Dario Graceffa, Martina Burlando, Anna Campanati, Elena Campione, Claudio Guarneri, Alessandra Narcisi, Paolo Pella, Paolo Romita, Massimo Travaglini and 43 more

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

53 authors.

Diego OrsiniSan Gallicano Dermatological Institute (IRCCS), 00144 Rome, Italy.ORCID 0000-0002-3190-3988
Dario GraceffaSan Gallicano Dermatological Institute (IRCCS), 00144 Rome, Italy.
Martina BurlandoSection of Dermatology, Department of Health Sciences (DiSSal), University of Genoa, 16126 Genoa, Italy.
Anna CampanatiDermatological Clinic, Department of Clinical and Molecular Sciences, Polytechnic Marche University, 60100 Ancona, Italy.
Elena CampioneDermatology, Department of Systems Medicine, University of Rome Tor Vergata, 00133 Rome, Italy.ORCID 0000-0001-7447-6798
Claudio GuarneriDepartment of Biomedical and Dental Sciences and Morpho Functional Imaging, Section of Dermatology, University of Messina, 98122 Messina, Italy.ORCID 0000-0003-3918-8779
Alessandra NarcisiDermatology Unit, IRCCS Humanitas Research Hospital, 10134 Rozzano, Italy.
Paolo PellaDermatology Unit, Ospedale degli Infermi, 13875 Biella, Italy.
Paolo RomitaSection of Dermatology and Venereology, Department of Precision and Regenerative Medicine and Ionian Area (DiMePre-J), University of Bari "Aldo Moro", 70124 Bari, Italy.
Massimo TravagliniU.O.S.D. Dermatologica-Centro Per La Cura Della Psoriasi, Ospedale A. Perrino, 72100 Brindisi, Italy.
Leonardo ZichichiDermatology Unit, Ospedale S A Antonio Abate, ASP Trapani, 91016 Erice, Italy.
Luisa Maria Halina ArancioFondazione IRCCS Cà Granda Ospedale Maggiore Policlinico Milano, ASST Crema, 20157 Milan, Italy.
Ginevra BagginiOutpatient Clinic, Section of Dermatology, ASL AL, 15100 Alessandria, Italy.
Riccardo BalestriDivision of Dermatology, Psoriasis Outpatient Service, APSS, 38122 Trento, Italy.ORCID 0000-0002-0885-054X
Tommaso BianchelliDermatological Clinic, Department of Clinical and Molecular Sciences, Polytechnic Marche University, 60100 Ancona, Italy.
Luca BianchiDermatology, Department of Systems Medicine, University of Rome Tor Vergata, 00133 Rome, Italy.ORCID 0000-0001-8697-6896
Alexandra Maria Giovanna BrunassoDepartment of Internal Medicine-Dermatology, Villa Scassi Hospital, ASL3, 16151 Genoa, Italy.ORCID 0000-0001-9122-9975
Anna Elisabetta CagniUnità Operativa Dipartimentale di Dermatologia e Venereologia, IRCCS San Gerardo, 20156 Milan, Italy.
Giacomo CaldarolaDermatology Unit, Agostino Gemelli University Polyclinic Foundation, IRCCS, 00168 Rome, Italy.ORCID 0000-0002-8837-9232
Gianluca CaliannoSection of Dermatology and Venereology, Department of Precision and Regenerative Medicine and Ionian Area (DiMePre-J), University of Bari "Aldo Moro", 70124 Bari, Italy.
Anton CarpentieriU.O.S.D. Dermatologica-Centro Per La Cura Della Psoriasi, Ospedale A. Perrino, 72100 Brindisi, Italy.
Martino CarrieroDermatology Outpatient, ASL Taranto, 74100 Taranto, Italy.
Andrea CarugnoDermatology Unit, Department of Medicine and Surgery, University of Insubria, 21100 Varese, Italy.ORCID 0000-0002-8231-2205
Franco ConaUmberto I, City Hospital of Enna, 94100 Enna, Italy.
Antonio CostanzoDermatology Unit, IRCCS Humanitas Research Hospital, 10134 Rozzano, Italy.
Emanuele Claudio CozzaniSection of Dermatology, Department of Health Sciences (DiSSal), University of Genoa, 16126 Genoa, Italy.
Giacomo Dal BelloSection of Dermatology, Department of Medicine, ASST di Mantova, 46100 Mantova, Italy.ORCID 0000-0002-5645-8403
Giovanni Carlo Lazzaro DanzusoU.O.S.D. Dermatologia, A.O. 'S.Elia'-Caltanissetta, 93100 Caltanissetta, Italy.
Annunziata DattolaDermatology Unit, Department of Clinical Internal, Anesthesiological and Cardiovascular Science, University of La Sapienza, 00161 Rome, Italy.ORCID 0000-0001-9504-5882
Marianna DonnarummaDermatology Unit, "Andrea Tortora" Hospital, ASL Salerno, 84098 Pagani, Italy.
Elena De ColUnit of Dermatology, Civil Hospital of Imperia, 18039 Imperia, Italy.
Maria EspositoDepartment of Biotechnological and Applied Clinical Sciences, University of L'Aquila, 67100 L'Aquila, Italy.ORCID 0000-0002-4773-6993
Carmen Silvia FiorellaDivision of Dermatology, Mons. Dimiccoli Hospital, 76121 Barletta, Italy.ORCID 0000-0002-3658-1543
Marco GalluzzoDermatology, Department of Systems Medicine, University of Rome Tor Vergata, 00133 Rome, Italy.ORCID 0000-0002-3424-5175
Francesca GraziolaDermatologic Clinic, AOU Maggiore della Carità Hospital, 28100 Novara, Italy.
Gaetano LicataDermatology Unit, Ospedale S A Antonio Abate, ASP Trapani, 91016 Erice, Italy.
Matteo LicciardelloSection of Dermatology, Koelliker Hospital, 10126 Turin, Italy.
Agostina LegoriUO Dermatologia IRCCS Ospedale Galeazzi & Università degli Studi di Milano, 20157 Milan, Italy.
Piergiorgio MalagoliDepartment of Dermatology, Dermatology Unit Azienda Ospedaliera San Donato Milanese, 20097 Milan, Italy.
Federica MolaDermatology Unit, ASST Lariana, 22020 Como, Italy.
Gaia MorettaDepartment of Dermatology, Istituto Dermopatico dell'Immacolata IRCCS Roma, 00167 Rome, Italy.ORCID 0000-0002-8839-5961
Andrea MuracchioliUnit of Dermatology, San Bartolomeo Hospital, 19042 La Spezia, Italy.
Attilia MusumeciU.O.S.D. Dermatologia, ARNAS Garibaldi, 95123 Catania, Italy.
Maria Letizia MusumeciUOC Dermatologia, University of Catania, PO "G. Rodolico", AOU Policlinico "G. Rodolico-San Marco", 95123 Catania, Italy.
Gianluca PagnanelliDepartment of Dermatology, Istituto Dermopatico dell'Immacolata IRCCS Roma, 00167 Rome, Italy.
Vincenzo PanasitiFondazione Policlinico Universitario Campus Bio Medico, 00128 Rome, Italy.
Lucia PeterleDepartment of Biomedical and Dental Sciences and Morpho Functional Imaging, Section of Dermatology, University of Messina, 98122 Messina, Italy.
Eugenio ProvenzanoDermatology Unit, Azienda Ospedaliera di Cosenza, 87100 Cosenza, Italy.
Marco RubattoDepartment of Medical Sciences, Section of Dermatology, University of Turin, 10126 Turin, Italy.ORCID 0000-0003-1706-656X
Oriele SarnoDepartment of Dermatology and Dermosurgery, AOSG San Giuseppe Moscati, 83100 Avellino, Italy.
Davide StrippoliDermatology Unit, Manzoni Hospital, ASST-Lecco, 23900 Lecco, Italy.
Fabrizio VairaUnit of Dermatology, IRCCS Ospedale San Raffaele, 20132 Milan, Italy.
Maria Concetta FargnoliSan Gallicano Dermatological Institute (IRCCS), 00144 Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

brodalumabfailureinterleukin-17 inhibitorsobesitypsoriasis

Identifiers

PMID40004618
PMCPMC11856090

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.