Evidence map›Paper›PMID 40004601›Full record

ArticleJournal of clinical medicine2025

Evaluation of Dose Reduction Factors and Impact on Progression-Free Survival in Patients Treated with CDK 4/6 Inhibitors.

Ali Kaan Güren, Murad Guliyev, Özkan Alan, Kıvanç Çadırci, İpek Naz Belevi, İlkay Gültürk, Emre Özge, Erkam Kocaaslan, Yeşim Ağyol, Pınar Erel and 11 more

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Genetic Variation inInternational journal of molecular sciences · 2026
    Article
  2. Observational
  3. Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Ali Kaan GürenDivision of Medical Oncology, Department of Internal Medicine, Marmara University School of Medicine, Istanbul 34854, Turkey.ORCID 0000-0002-3562-5006
Murad GuliyevDivision of Medical Oncology, Department of Internal Medicine, Cerrahpasa Medical Faculty, Istanbul University-Cerrahpasa, Istanbul 34093, Turkey.
Özkan AlanDivision of Medical Oncology, Department of Internal Medicine, Cerrahpasa Medical Faculty, Istanbul University-Cerrahpasa, Istanbul 34093, Turkey.ORCID 0000-0002-6635-2012
Kıvanç ÇadırciDepartment of Internal Medicine, Marmara University School of Medicine, Istanbul 34854, Turkey.
İpek Naz BeleviDepartment of Internal Medicine, Marmara University School of Medicine, Istanbul 34854, Turkey.
İlkay GültürkDepartment of Medical Oncology, Istanbul Research and Training Hospital, Istanbul 34093, Turkey.
Emre ÖzgeDepartment of Medical Oncology, Istanbul Research and Training Hospital, Istanbul 34093, Turkey.
Erkam KocaaslanDivision of Medical Oncology, Department of Internal Medicine, Marmara University School of Medicine, Istanbul 34854, Turkey.
Yeşim AğyolDivision of Medical Oncology, Department of Internal Medicine, Marmara University School of Medicine, Istanbul 34854, Turkey.
Pınar ErelDivision of Medical Oncology, Department of Internal Medicine, Marmara University School of Medicine, Istanbul 34854, Turkey.
Burak PaçacıDivision of Medical Oncology, Department of Internal Medicine, Marmara University School of Medicine, Istanbul 34854, Turkey.
Mustafa Alperen TunçDivision of Medical Oncology, Department of Internal Medicine, Marmara University School of Medicine, Istanbul 34854, Turkey.ORCID 0000-0002-1537-3032
Nargiz MajidovaDivision of Medical Oncology, Department of Internal Medicine, Marmara University School of Medicine, Istanbul 34854, Turkey.
Nadiye SeverDivision of Medical Oncology, Department of Internal Medicine, Marmara University School of Medicine, Istanbul 34854, Turkey.ORCID 0000-0001-7312-3827
Abdussamet ÇelebiDivision of Medical Oncology, Department of Internal Medicine, Marmara University School of Medicine, Istanbul 34854, Turkey.
Rukiye Arıkan ErdoğanDivision of Medical Oncology, Department of Internal Medicine, Marmara University School of Medicine, Istanbul 34854, Turkey.
Selver IşıkDivision of Medical Oncology, Department of Internal Medicine, Marmara University School of Medicine, Istanbul 34854, Turkey.
Nebi Serkan DemirciDivision of Medical Oncology, Department of Internal Medicine, Cerrahpasa Medical Faculty, Istanbul University-Cerrahpasa, Istanbul 34093, Turkey.
Murat SarıDivision of Medical Oncology, Department of Internal Medicine, Marmara University School of Medicine, Istanbul 34854, Turkey.ORCID 0000-0003-0596-1559
Osman KöstekDivision of Medical Oncology, Department of Internal Medicine, Marmara University School of Medicine, Istanbul 34854, Turkey.
İbrahim Vedat BayoğluDivision of Medical Oncology, Department of Internal Medicine, Marmara University School of Medicine, Istanbul 34854, Turkey.ORCID 0000-0002-0481-1084

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CDK 4/6 inhibitorsdose reductionpalbociclibribociclib

Identifiers

PMID40004601
PMCPMC11856098

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.