Evidence map›Paper›PMID 40004320›Full record

ArticleMaterials (Basel, Switzerland)2025

High-Level Lanthanide-Doped Upconversion Nanoparticles-Based Aptasensor to Increase Carcinoembryonic Antigen Detection Sensitivity.

Lujun Niu, Qiren Sun, Shijia Wei, Dixiang Gong, Enhui Wang, Yan Chen, Lu Xia, Xingyu Liu, Langping Tu, Long Shao and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Lujun NiuKey Laboratory of Automobile Materials of Ministry of Education, Department of Materials Science and Engineering, Jilin University, Changchun 130022, China.
Qiren SunKey Laboratory of Automobile Materials of Ministry of Education, Department of Materials Science and Engineering, Jilin University, Changchun 130022, China.
Shijia WeiKey Laboratory of Automobile Materials of Ministry of Education, Department of Materials Science and Engineering, Jilin University, Changchun 130022, China.
Dixiang GongDepartment of Mechanical Engineering, McGill University, Montreal, QC H3A 0C3, Canada.
Enhui WangKey Laboratory of Automobile Materials of Ministry of Education, Department of Materials Science and Engineering, Jilin University, Changchun 130022, China.
Yan ChenKey Laboratory of Automobile Materials of Ministry of Education, Department of Materials Science and Engineering, Jilin University, Changchun 130022, China.
Lu XiaThe 49th Research Institute of China Electronics Technology Group Corporation, Harbin 150028, China.
Xingyu LiuThe 49th Research Institute of China Electronics Technology Group Corporation, Harbin 150028, China.
Langping TuSchool of Materials Science and Engineering, Changchun University of Science and Technology, Changchun 130022, China.
Long ShaoSchool of Materials Science and Engineering, Changchun University of Science and Technology, Changchun 130022, China.
Hongfei LiSchool of Materials Science and Engineering, Changchun University of Science and Technology, Changchun 130022, China.
Jing ZuoKey Laboratory of Automobile Materials of Ministry of Education, Department of Materials Science and Engineering, Jilin University, Changchun 130022, China.

Funding

the Jilin Provincial Department of Science and Technology 20240101319JCthe Laoshan Laboratory LSKJ202203601the National Key R&D Program of China 2023YFC2811205the National Natural Science Foundation of China 12104179, 12474416, 62305045, 12204192
6 · The paper itself

Abstract

Boosting the accuracy and speed of cancer detection is highly desirous in tumor detection, and sensors capable of detecting carcinoembryonic antigen (CEA) have great application prospects in this field. A highly sensitive sensor is constructed based on the fluorescence resonance energy transfer (FRET) with heavily rare-earth-doped upconversion nanoparticles (UCNPs) as energy donors and polydopamine nanoparticles (PDA NPs) as energy acceptors. This sensor detects the fluctuations in CEA molecules via luminescence quenching and recovery resulting from a competitive binding assay between CEA and PDA NPs. The high-level-doped design of UCNPs (i.e., NaYF

Indexed as

CEA detectionFREThigh-level dopingUCNPs-PDA NP sensor

Identifiers

PMID40004320
PMCPMC11857722

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.