Evidence map›Paper›PMID 40004125›Full record

ArticleInternational journal of molecular sciences2025

Polymorphic Variants of Peptidylarginine Deiminase Gene from

Karolina Strzelec, Agata Dziedzic-Kowalska, Łukasz Sieron, Grzegorz P Bereta, Karolina L Stepien, Klara Ferenc, Katarzyna Łazarz-Bartyzel, Iwona Olszewska-Czyż, Iwona Rąpalska, Małgorzata Aptekorz and 3 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Pathogenesis ofFrontiers in cellular and infection microbiology · 2026
    Review
  2. Pathogenicity ofFrontiers in cellular and infection microbiology · 2026
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Karolina StrzelecDepartment of Molecular Biology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, 40-752 Katowice, Poland.ORCID 0000-0002-3393-1413
Agata Dziedzic-KowalskaDepartment of Molecular Biology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, 40-752 Katowice, Poland.
Łukasz SieronDepartment of Medical Genetics, Faculty of Medical Sciences in Katowice, Medical University of Silesia, 40-752 Katowice, Poland.ORCID 0000-0003-4512-718X
Grzegorz P BeretaMalopolska Centre of Biotechnology, Jagiellonian University, 30-387 Krakow, Poland.ORCID 0000-0002-2925-7796
Karolina L StepienDepartment of Molecular Biology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, 40-752 Katowice, Poland.ORCID 0000-0002-6934-8780
Klara FerencDepartment of Molecular Biology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, 40-752 Katowice, Poland.ORCID 0009-0005-8885-0855
Katarzyna Łazarz-BartyzelDepartment of Periodontology, Preventive Dentistry and Oral Pathology, Faculty of Medicine, Medical College, Jagiellonian University, 31-155 Krakow, Poland.
Iwona Olszewska-CzyżDepartment of Periodontology, Preventive Dentistry and Oral Pathology, Faculty of Medicine, Medical College, Jagiellonian University, 31-155 Krakow, Poland.ORCID 0000-0002-9023-0824
Iwona RąpalskaDepartment of Oral Surgery, Medical College, Jagiellonian University, 31-155 Krakow, Poland.
Małgorzata AptekorzDepartment of Medical Microbiology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, 40-752 Katowice, Poland.ORCID 0000-0002-7343-4702
Tomasz KaczmarzykDepartment of Oral Surgery, Medical College, Jagiellonian University, 31-155 Krakow, Poland.ORCID 0000-0003-3024-9926
Marta Cześnikiewicz-GuzikDepartment of Periodontology, Preventive Dentistry and Oral Pathology, Faculty of Medicine, Medical College, Jagiellonian University, 31-155 Krakow, Poland.ORCID 0000-0002-7444-1373
Katarzyna GawronDepartment of Molecular Biology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, 40-752 Katowice, Poland.ORCID 0000-0003-3430-6270

Funding

Medical University of Silesia in Katowice BNW-2-056/N/4/OMedical University of Silesia in Katowice BNW-2-095/N/3/OMedical University of Silesia in Katowice PCN-1-232/N/2/OMedical University of Silesia in Katowice PCN-2-097-N/1/INational Science Center UMO-2012/07/B/NZ6/03524National Science Center UMO-2018/29/B/NZ2/01930
6 · The paper itself

Abstract

Periodontitis (PD), an oral inflammatory disease, is primarily caused by

Indexed as

Bacterial ProteinsPeriodontitisPolymorphism, GeneticPorphyromonas gingivalisProtein-Arginine DeiminasesFemaleHumansMaleVirulenceBacterial ProteinsProtein-Arginine Deiminasesgene sequencegene variabilitypeptidylarginine deiminaseperiodontitisPGE2-dependent pathwayP. gingivalispro-inflammatory cytokinesvirulence factors

Identifiers

PMID40004125
PMCPMC11855631

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.