Evidence map›Paper›PMID 40004095›Full record

ReviewInternational journal of molecular sciences2025

The Aryl Hydrocarbon Receptor (AHR): Peacekeeper of the Skin.

Hannah R Dawe, Paola Di Meglio

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
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  9. Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Protective Effects ofCurrent issues in molecular biology · 2025
    Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hannah R DaweSt John's Institute of Dermatology, King's College London, London SE1 9RT, UK.
Paola Di MeglioSt John's Institute of Dermatology, King's College London, London SE1 9RT, UK.ORCID 0000-0002-2066-7780

Funding

Medical Research Council MR/W006820/1National Psoriasis Foundation 814364Psoriasis Association ST1/19Psoriasis Association ST1/23
6 · The paper itself

Abstract

In the last decade, the aryl hydrocarbon receptor (AHR) has emerged as a critical peacekeeper for the maintenance of healthy skin. The evolutionary conservation of AHR implied physiological functions for this receptor, beyond the detoxification of man-made compounds, a notion further supported by the existence of physiological AHR ligands, notably derivates of tryptophan by the host and host microbiome. The UV light-derived ligand, 6-formylindolo[3,2-

Indexed as

Receptors, Aryl HydrocarbonSkinAnimalsCarbazolesHumansPsoriasisSignal Transduction6-formylindolo(3,2-b)carbazoleCarbazolesReceptors, Aryl Hydrocarbonaryl hydrocarbon receptoratopic dermatitispsoriasisskinskin inflammationtapinarof

Identifiers

PMID40004095
PMCPMC11855870

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.