Evidence map›Paper›PMID 40004070›Full record

ArticleInternational journal of molecular sciences2025

Hepatoprotective Activity of Nature-Derived Polyphenols Studied by Mass Spectrometry Based Multi-OMICS Approach.

Alexander G Brzhozovskiy, Savva D Semenov, Alexander Y Zherebker, Anna E Bugrova, Maria N Yurova, Yury V Zhernov, Oxana A Kovaleva, Alexander L Semenov, Dmitry P Abroskin, Stepan S Kruglov and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Alexander G BrzhozovskiyProject Center of Omics Technologies and Advanced Mass Spectrometry, 121205 Moscow, Russia.
Savva D SemenovProject Center of Omics Technologies and Advanced Mass Spectrometry, 121205 Moscow, Russia.
Alexander Y ZherebkerProject Center of Omics Technologies and Advanced Mass Spectrometry, 121205 Moscow, Russia.ORCID 0000-0002-3481-4606
Anna E BugrovaProject Center of Omics Technologies and Advanced Mass Spectrometry, 121205 Moscow, Russia.ORCID 0000-0003-1515-9447
Maria N YurovaProject Center of Omics Technologies and Advanced Mass Spectrometry, 121205 Moscow, Russia.ORCID 0000-0003-3589-5871
Yury V ZhernovProject Center of Omics Technologies and Advanced Mass Spectrometry, 121205 Moscow, Russia.ORCID 0000-0001-8734-5527
Oxana A KovalevaProject Center of Omics Technologies and Advanced Mass Spectrometry, 121205 Moscow, Russia.
Alexander L SemenovN.N. Petrov National Medical Research Center of Oncology, 197758 Saint Petersburg, Russia.
Dmitry P AbroskinProject Center of Omics Technologies and Advanced Mass Spectrometry, 121205 Moscow, Russia.
Stepan S KruglovN.N. Petrov National Medical Research Center of Oncology, 197758 Saint Petersburg, Russia.
Elena I FedorosN.N. Petrov National Medical Research Center of Oncology, 197758 Saint Petersburg, Russia.ORCID 0000-0002-2426-9843
Alexey S KononikhinProject Center of Omics Technologies and Advanced Mass Spectrometry, 121205 Moscow, Russia.ORCID 0000-0002-2238-3458
Evgeniy N NikolaevProject Center of Omics Technologies and Advanced Mass Spectrometry, 121205 Moscow, Russia.

Funding

Russian Science Foundation 22-75-10140
6 · The paper itself

Abstract

The aim of this study was to examine the hepatoprotective activity of multicomponent mixtures of natural origin in the BALB/C mouse model, with subacute liver failure (SALF) induced by the administration of toxin carbon tetrachloride (CCl

Indexed as

LiverPolyphenolsProtective AgentsAnimalsCarbon TetrachlorideChemical and Drug Induced Liver InjuryDisease Models, AnimalMaleMass SpectrometryMetabolomeMetabolomicsMiceMice, Inbred BALB CMultiomicsPlant ExtractsPlant RootsCarbon TetrachloridePlant ExtractsPolyphenolsProtective Agentsbiomarkerslivermass spectrometrymiceproteomics

Identifiers

PMID40004070
PMCPMC11855638

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.