Evidence map›Paper›PMID 40003988›Full record

ArticleInternational journal of molecular sciences2025

Liquid Chromatography Quadrupole Time-of-Flight Tandem Mass Spectrometry Characterization of Ethyl Acetate Fraction from

Wook-Chul Kim, Hyeon Kang, Seung-Hong Lee

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Ethanolic Extract ofInternational journal of molecular sciences · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Wook-Chul KimDepartment of Medical Science, Soonchunhyang University, Asan 31538, Republic of Korea.ORCID 0009-0002-5296-0620
Hyeon KangDepartment of Medical Science, Soonchunhyang University, Asan 31538, Republic of Korea.ORCID 0009-0003-6912-8643
Seung-Hong LeeDepartment of Medical Science, Soonchunhyang University, Asan 31538, Republic of Korea.ORCID 0000-0003-2823-8718

Funding

Korea Innovation Foundation funded 2023-DD-UP-0007
6 · The paper itself

Abstract

Melanin overproduction causes various skin diseases, such as spots, freckles, and wrinkles, resulting in the requirement of melanin synthesis inhibitors like 1-phenyl-2-thiourea (PTU) and kojic acid, which have been commonly used in the pharmaceutical industry. However, these inhibitors can cause side effects such as skin irritation and allergies. Therefore, it is necessary to develop safe and effective melanin inhibitors from natural resources. The purpose of this study was to investigate a whitening agent from natural substances using B16F10 melanoma cells and zebrafish model. We investigated the melanogenesis-inhibiting activities of the fractions from

Indexed as

MelaninsMelanoma, ExperimentalPlant ExtractsSargassumAcetatesAnimalsCell Line, TumorChromatography, LiquidMiceMonophenol MonooxygenaseTandem Mass SpectrometryZebrafishAcetatesethyl acetateMelaninsMonophenol MonooxygenasePlant ExtractsB16F10 melanoma cellsethyl acetate fractionmelanogenesisSargassum pallidumzebrafish

Identifiers

PMID40003988
PMCPMC11855592

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.