ArticleInternational journal of molecular sciences2025
Changes in the Level of hs-CRP in the Blood and Morphometric Parameters of Tissues Following Implantation of Polypropylene.
Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Autoimmune syndrome induced by adjuvants (ASIA) following urethral sling placement: A case report.Case reports in women's health · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In recent decades, the use of polypropylene meshes has been the gold standard in the surgical treatment of muscular corset failure. However, the reasons behind the low percentage of complications and recurrences remain controversial. Tissue hyperreactivity and the immune response to polypropylene may be contributing factors. Measurements of the level of hs-CRP (highly sensitive C-reactive protein) in the blood and morphometric studies of tissues around the implant were carried out for three months after the installation of polypropylene implants in 53 laboratory rats. The research results confirmed the good biocompatibility of polypropylene and the formation of full-fledged connective tissue around polypropylene three months after the installation of the material. The level of hs-CRP in the blood increased slightly, without significant differences, but in some animals, there was a sharp increase in this indicator at 3 months. Such results may indicate the development of hyperreactivity to the implantation of a synthetic material and, with other accompanying factors, lead to the development of complications both at the local tissue and general immune levels.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.