Evidence map›Paper›PMID 40003877›Full record

ArticleInternational journal of molecular sciences2025

Cardiac MRI Strain as an Early Indicator of Myocardial Dysfunction in Hypertrophic Cardiomyopathy.

Siqin Liu, Oumaima Laghzali, Shahriar Shalikar, Mara-Camelia Rusu, Lucie Carrier, Thoralf Niendorf, Min-Chi Ku

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Multimodality imaging in hypertrophic cardiomyopathy.Journal of cardiovascular imaging · 2026
    Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Siqin LiuMax-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin Ultrahigh Field Facility (B.U.F.F.), 13125 Berlin, Germany.ORCID 0000-0003-2817-892X
Oumaima LaghzaliMax-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin Ultrahigh Field Facility (B.U.F.F.), 13125 Berlin, Germany.ORCID 0000-0001-5923-6710
Shahriar ShalikarMax-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin Ultrahigh Field Facility (B.U.F.F.), 13125 Berlin, Germany.
Mara-Camelia RusuTechnology Platform Electron Microscopy, Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), 13125 Berlin, Germany.ORCID 0000-0002-8369-3580
Lucie CarrierDepartment of Experimental Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0000-0001-8776-5820
Thoralf NiendorfMax-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin Ultrahigh Field Facility (B.U.F.F.), 13125 Berlin, Germany.ORCID 0000-0001-7584-6527
Min-Chi KuMax-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin Ultrahigh Field Facility (B.U.F.F.), 13125 Berlin, Germany.ORCID 0000-0003-0963-2461

Funding

Deutsche Forschungsgemeinschaft CA 618/9-1Deutsche Forschungsgemeinschaft KU 3722/4-1Deutsche Forschungsgemeinschaft WA 2804/7-1
6 · The paper itself

Abstract

Hypertrophic cardiomyopathy (HCM) is often characterized by augmented cardiac contractility, which frequently remains undetectable in its early stages. Emerging evidence suggests that hypercontractility is linked to mitochondrial defects that develop early in HCM progression. However, imaging markers for identifying these early alterations in myocardial function are lacking. We used cardiac magnetic resonance feature tracking (CMR-FT) to assess myocardial strain in a

Indexed as

Cardiomyopathy, HypertrophicMagnetic Resonance ImagingMyocardiumAnimalsCarrier ProteinsDisease Models, AnimalFemaleHumansMaleMiceMyocardial ContractionMyosin Binding Protein CCarrier ProteinsMyosin Binding Protein Ccardiac dysfunctioncardiomyopathycontractilityimaging markersmagnetic resonance imagingmyocardial remodelingstrain

Identifiers

PMID40003877
PMCPMC11855820

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.