Evidence map›Paper›PMID 40003875›Full record

ArticleInternational journal of molecular sciences2025

Mutations in Filamin C Associated with Both Alleles Do Not Affect the Functioning of Mice Cardiac Muscles.

Leonid A Ilchuk, Ksenia K Kochegarova, Iuliia P Baikova, Polina D Safonova, Alexandra V Bruter, Marina V Kubekina, Yulia D Okulova, Tatiana E Minkovskaya, Nadezhda A Kuznetsova, Daria M Dolmatova and 7 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Generation of Stra8-Cre/ERT2 Mouse Activator Strain for Inducible Cre-lox Recombination in Spermatocytes.Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Leonid A IlchukCenter for Precision Genome Editing and Genetic Technologies for Biomedicine, Institute of Gene Biology, Russian Academy of Sciences, 119334 Moscow, Russia.ORCID 0000-0002-0157-2102
Ksenia K KochegarovaInstitute for Regenerative Medicine, Sechenov University, 119991 Moscow, Russia.
Iuliia P BaikovaCenter for Precision Genome Editing and Genetic Technologies for Biomedicine, Institute of Gene Biology, Russian Academy of Sciences, 119334 Moscow, Russia.ORCID 0000-0002-1901-3640
Polina D SafonovaCore Facility Center, Institute of Gene Biology, Russian Academy of Sciences, 119334 Moscow, Russia.
Alexandra V BruterCenter for Precision Genome Editing and Genetic Technologies for Biomedicine, Institute of Gene Biology, Russian Academy of Sciences, 119334 Moscow, Russia.
Marina V KubekinaCenter for Precision Genome Editing and Genetic Technologies for Biomedicine, Institute of Gene Biology, Russian Academy of Sciences, 119334 Moscow, Russia.
Yulia D OkulovaCenter for Precision Genome Editing and Genetic Technologies for Biomedicine, Institute of Gene Biology, Russian Academy of Sciences, 119334 Moscow, Russia.
Tatiana E MinkovskayaCenter for Precision Genome Editing and Genetic Technologies for Biomedicine, Institute of Gene Biology, Russian Academy of Sciences, 119334 Moscow, Russia.
Nadezhda A KuznetsovaCenter for Precision Genome Editing and Genetic Technologies for Biomedicine, Institute of Gene Biology, Russian Academy of Sciences, 119334 Moscow, Russia.
Daria M DolmatovaCenter for Precision Genome Editing and Genetic Technologies for Biomedicine, Institute of Gene Biology, Russian Academy of Sciences, 119334 Moscow, Russia.ORCID 0000-0002-8396-2672
Anna Yu RyabininaV.A. Frolov Department of General Pathology and Pathological Physiology, Institute of Medicine, Peoples' Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya Street, 117198 Moscow, Russia.
Andrey A MozhaevLaboratory of Molecular Technologies, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.ORCID 0000-0001-5790-9926
Vsevolod V BelousovLaboratory of Molecular Technologies, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.
Boris P ErshovInstitute for Regenerative Medicine, Sechenov University, 119991 Moscow, Russia.
Peter S TimashevInstitute for Regenerative Medicine, Sechenov University, 119991 Moscow, Russia.
Maxim A FilatovCenter for Precision Genome Editing and Genetic Technologies for Biomedicine, Institute of Gene Biology, Russian Academy of Sciences, 119334 Moscow, Russia.
Yulia Yu SilaevaCenter for Precision Genome Editing and Genetic Technologies for Biomedicine, Institute of Gene Biology, Russian Academy of Sciences, 119334 Moscow, Russia.

Funding

The Ministry of Science and Higher Education of the Russian Federation 075-15-2019-1661
6 · The paper itself

Abstract

Filamin C (FLNC) is a structural protein of muscle fibers. Mutations in the

Indexed as

FilaminsMutationMyocardiumAllelesAnimalsCRISPR-Cas SystemsFemaleHeterozygoteHomozygoteMaleMiceMuscle, SkeletalFilaminsanimal modelcardiomyopathyfilamin Cflnc

Identifiers

PMID40003875
PMCPMC11855563

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.