Evidence map›Paper›PMID 40003723›Full record

ReviewLife (Basel, Switzerland)2025

Weight-Bearing Versus Non-Weight-Bearing After Ankle Fracture: A Systematic Review and Meta-Analysis of Patient-Reported Outcome.

Rafael Llombart-Blanco, Gonzalo Mariscal, Ibrahim Khalil, Violeta Cordón, María Benlloch, Carlos Barrios, Rafael Llombart-Ais

Abstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rafael Llombart-BlancoOrthopedic Surgery Department, University Clinic of Navarra, 31008 Pamplona, Spain.ORCID 0000-0002-8790-0428
Gonzalo MariscalInstitute for Research on Musculoskeletal Disorders, School of Medicine, Valencia Catholic University, 46001 Valencia, Spain.ORCID 0000-0002-5166-198X
Ibrahim KhalilFaculty of Medicine, Alexandria University, Alexandria 21526, Egypt.
Violeta CordónInstitute for Research on Musculoskeletal Disorders, School of Medicine, Valencia Catholic University, 46001 Valencia, Spain.
María BenllochDepartment of Basic Biomedical Sciences, Catholic University of Valencia, 46001 Valencia, Spain.ORCID 0000-0002-3342-6732
Carlos BarriosInstitute for Research on Musculoskeletal Disorders, School of Medicine, Valencia Catholic University, 46001 Valencia, Spain.ORCID 0000-0002-6657-7246
Rafael Llombart-AisInstitute for Research on Musculoskeletal Disorders, School of Medicine, Valencia Catholic University, 46001 Valencia, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnkle fractures commonly affect mobility and quality of life. Although unstable fractures typically require surgery, post-treatment protocols vary widely, including both surgical and conservative approaches. This systematic review and meta-analysis evaluated the effects of early weight-bearing after ankle fracture treatment on functional outcomes and quality of life.

methodsFollowing the PRISMA guidelines and the PICOS strategy, we performed a meta-analysis across multiple databases (PubMed, Embase, Scopus, and Cochrane Library). Analysis was conducted using Review Manager 5.4, calculating the mean and standard mean differences with 95% confidence intervals (CIs).

resultsEleven studies (

conclusionThe outcomes obtained indicated statistically significant differences in favor of the early weight-bearing group regarding ankle function and quality of life.

Indexed as

ankle fractureimmobilizationmeta-analysispatient-reported outcomesweight bear

Identifiers

PMID40003723
PMCPMC11857458

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.