Evidence map›Paper›PMID 40003718›Full record

ArticleLife (Basel, Switzerland)2025

Health Benefits of Montmorency Tart Cherry Juice Supplementation in Adults with Mild to Moderate Ulcerative Colitis; A Placebo Randomized Controlled Trial.

Jonathan Sinclair, Graham McLaughlin, Robert Allan, Johanne Brooks-Warburton, Charlotte Lawson, Shan Goh, Terun Desai, Lindsay Bottoms

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jonathan SinclairResearch Centre for Applied Sport, Physical Activity and Performance, School of Health Social Work & Sport, University of Central Lancashire, Preston PR1 2HE, UK.ORCID 0000-0002-2231-3732
Graham McLaughlinSchool of Life and Medical Sciences, University of Hertfordshire, Hatfield AL10 9AB, UK.
Robert AllanResearch Centre for Applied Sport, Physical Activity and Performance, School of Health Social Work & Sport, University of Central Lancashire, Preston PR1 2HE, UK.
Johanne Brooks-WarburtonSchool of Life and Medical Sciences, University of Hertfordshire, Hatfield AL10 9AB, UK.
Charlotte LawsonSchool of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston PR1 2HE, UK.
Shan GohDepartment of Clinical, Pharmaceutical and Biological Science, School of Life and Medical Sciences, University of Hertfordshire, Hatfield AL10 9AB, UK.
Terun DesaiDivision of Surgery & Interventional Science, University College London, London WC1E 6BT, UK.
Lindsay BottomsSchool of Life and Medical Sciences, University of Hertfordshire, Hatfield AL10 9AB, UK.ORCID 0000-0003-4632-3764

Funding

Cherry Marketing Institute N/A
6 · The paper itself

Abstract

aimsUlcerative colitis (UC) significantly impacts individuals' self-perception, body image, and overall quality of life, while also imposing considerable economic costs. These challenges highlight the necessity for complementary therapeutic strategies with reduced adverse effects to support conventional pharmacological treatments. Among natural interventions, Montmorency tart cherries, noted for their high anthocyanin content have emerged as a natural anti-inflammatory agent for UC. The current trial aimed to investigate the effects of Montmorency tart cherries compared to placebo in patients with mild to moderate UC. MATERIALS AND

methodsThirty-five patients with UC were randomly assigned to receive either placebo or Montmorency tart cherry juice, of which they drank 60 mL per day for 6 weeks. The primary outcomes and health-related quality of life, measured via the Inflammatory Bowel Disease Quality of Life Questionnaire (IBDQ), and the secondary measures, including other health-related questionnaires, blood biomarkers, and faecal samples, were measured before and after the intervention. Linear mixed-effects models were adopted to contrast the changes from baseline to 6 weeks between trial arms. Effect sizes were calculated using Cohen's

resultsThere were significantly greater improvements in the IBDQ (22.61 (95% CI = 5.24 to 39.99)

conclusionsGiven the profoundly negative effects of UC on health-related quality of life and its fiscal implications for global healthcare systems, this trial indicates that twice-daily tart cherry supplementation can improve IBD-related quality of life as well as the severity of symptoms and therefore may be important in the management of UC.

Indexed as

complementary medicineinflammatory bowel diseaseMontmorency tart cherryrandomised controlled trialulcerative colitis

Identifiers

PMID40003718
PMCPMC11857002

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.