Evidence map›Paper›PMID 40003702›Full record

ReviewLife (Basel, Switzerland)2025

Cardiac Metastasis: Epidemiology, Pathophysiology, and Clinical Management.

Fabiana Lucà, Iris Parrini, Maria Laura Canale, Carmelo Massimiliano Rao, Mariacarmela Nucara, Giuseppe Pelaggi, Adriano Murrone, Stefano Oliva, Irma Bisceglia, Andrea Sergi and 9 more

Abstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  18. Incidental Cardiac Metastasis in Breast Carcinoma.Diagnostics (Basel, Switzerland) · 2025
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Fabiana LucàCardiology Department, Grande Ospedale Metropolitano di Reggio Calabria, Bianchi Malacrino Morelli Hospital, 89129 Reggio Calabria, Italy.ORCID 0000-0002-5369-5382
Iris ParriniCardiology Department, Mauriziano Hospital, 10128 Torino, Italy.ORCID 0000-0002-0038-9445
Maria Laura CanaleDivision of Cardiology, Azienda USL Toscana Nord-Ovest, Versilia Hospital, 55041 Lido di Camaiore, Italy.
Carmelo Massimiliano RaoDivision of Cardiology, Santa Maria Degli Ungheresi Hospital, 89024 Polistena, Italy.
Mariacarmela NucaraCardiology Department, Grande Ospedale Metropolitano di Reggio Calabria, Bianchi Malacrino Morelli Hospital, 89129 Reggio Calabria, Italy.
Giuseppe PelaggiCardiology Department, Grande Ospedale Metropolitano di Reggio Calabria, Bianchi Malacrino Morelli Hospital, 89129 Reggio Calabria, Italy.
Adriano MurroneCardiology Unit, Città di Castello Hospital, 06012 Città di Castello, Italy.ORCID 0000-0003-3184-1921
Stefano OlivaCardiology Unit, IRCCS Istituto Tumori "Giovanni Paolo II", 70124 Bari, Italy.ORCID 0000-0002-3200-2372
Irma BiscegliaIntegrated Cardiology Services, Department of Cardio-Thoracic-Vascular, Azienda Ospedaliera San Camillo Forlanini, 00152 Rome, Italy.ORCID 0000-0002-0689-0695
Andrea SergiRadiology Unity, Grande Ospedale Metropolitano di Reggio Calabria, 89129 Reggio Calabria, Italy.
Giovanna GeraciCardiology Department, Sant'Antonio Abate Hospital, ASP Trapani, 91100 Erice, Italy.ORCID 0000-0003-0092-8717
Carmine RiccioCardiovascular Department, Sant'Anna e San Sebastiano Hospital, 95122 Caserta, Italy.
Roberto CeravoloCardiology Unit, Giovanni Paolo II Hospital, 88046 Lamezia, Italy.
Sandro GelsominoCardiovascular Research Institute, Maastricht University, 6211 LK Maastricht, The Netherlands.ORCID 0000-0002-7746-989X
Furio ColivicchiClinical and Rehabilitation Cardiology Department, San Filippo Neri Hospital, ASL Roma 1, 00193 Roma, Italy.
Massimo GrimaldiCardiology Department, F. Miulli Hospital, Acquaviva delle Fonti, 70021 Bari, Italy.ORCID 0000-0002-9347-8884
Fabrizio OlivaCardiology Unit, ASST Grande Ospedale Metropolitano Niguarda, 20162 Milano, Italy.
Michele Massimo GuliziaCardiology Department, Garibaldi Nesima Hospital, 95122 Catania, Italy.
Multi-Specialist and Multi-Integrated Approach in Cardiology Working Group, Cardio-Oncology Working Group, Cardiogeriatrics Working Group of Italian Association of Hospital Cardiologists and Epidemiology Working Group (ANMCO)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac metastases (CMs) are more common than primary cardiac tumors, with autopsy studies reporting incidence rates between 2.3% and 18.3%. Their increasing detection is largely attributed to advances in cancer treatments, which have extended patient survival. CMs may present with diverse clinical manifestations depending on their size, location, and extent of infiltration, although they often remain asymptomatic and are identified only postmortem. Sometimes, they are incidentally discovered during tumor staging or follow-up evaluations. This review explores the incidence, pathophysiology, clinical features, and potential complications of CMs, focusing on their prevalence and characteristics. It highlights the importance of early detection and optimized management strategies to address this growing clinical concern. Further research is essential to elucidate the mechanisms driving CMs and develop effective therapeutic interventions.

Indexed as

cardiac tumorsdiagnostic methodheartmetastatic tumors

Identifiers

PMID40003702
PMCPMC11857090

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.