Evidence map›Paper›PMID 40003687›Full record

ArticleLife (Basel, Switzerland)2025

Evaluation of Static and Dynamic Pupil and Light Sensitivity to a Single Drop of Various Concentrations of Low-Dose Atropine (0.01%, 0.025%, and 0.05%).

Muteb K Alanazi, Abdulmalik Almansour, Sarah S Almutairi, Ahmad Alharbi, Mohammed S Alhazmi, Ali Almustanyir, Basal H Altoaimi, Meznah S Almutairi, Mona M Alamri, Maria Liu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Life (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Muteb K AlanaziOptometry Department, College of Applied Medical Sciences, King Saud University, Riyadh 11362, Saudi Arabia.ORCID 0000-0003-2994-1472
Abdulmalik AlmansourOptometry Department, College of Applied Medical Sciences, King Saud University, Riyadh 11362, Saudi Arabia.
Sarah S AlmutairiOptometry Department, College of Applied Medical Sciences, King Saud University, Riyadh 11362, Saudi Arabia.
Ahmad AlharbiOptometry Department, College of Applied Medical Sciences, King Saud University, Riyadh 11362, Saudi Arabia.
Mohammed S AlhazmiOptometry Department, College of Applied Medical Sciences, King Saud University, Riyadh 11362, Saudi Arabia.ORCID 0009-0007-6204-5430
Ali AlmustanyirOptometry Department, College of Applied Medical Sciences, King Saud University, Riyadh 11362, Saudi Arabia.ORCID 0000-0002-3225-3075
Basal H AltoaimiOptometry Department, College of Applied Medical Sciences, King Saud University, Riyadh 11362, Saudi Arabia.ORCID 0000-0002-2101-7675
Meznah S AlmutairiOptometry Department, College of Applied Medical Sciences, King Saud University, Riyadh 11362, Saudi Arabia.ORCID 0000-0003-1802-2403
Mona M AlamriOptometry Department, College of Applied Medical Sciences, King Saud University, Riyadh 11362, Saudi Arabia.
Maria LiuSchool of Optometry, University of California, Berkeley, CA 94720, USA.

Funding

King Saud University Researcher Supporting Project (RSPD2024R882)
6 · The paper itself

Abstract

This study aimed to evaluate the static and dynamic pupil changes, and light sensitivity following a single dose of low-dose atropine at concentrations of 0.01%, 0.025%, and 0.05% over a 24 h period. Healthy young adults (20-22 years; n = 25) participated in this randomized, double-blind study. Each participant received one of three atropine concentrations in a masked fashion. Baseline mesopic and dynamic pupil sizes were measured at various post-instillation intervals (5 min, 30 min, 1 h, 2 h, 4 h, and 24 h). A minimum 48 h washout period was observed between treatments. Subjective light sensitivity was assessed using the Visual Light Sensitivity Questionnaire (VLSQ-8) at 24 h. All atropine concentrations caused significant pupil dilation (

Indexed as

dynamic pupillight sensitivitylow-dose atropinepupil

Identifiers

PMID40003687
PMCPMC11856749

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.