ReviewLife (Basel, Switzerland)2025
Anatomical-Based Filler Injection Diagnosis to Treatment Techniques: Infraorbital Groove and Hollowness.
Review in Life (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Ultrasound-guided Minimally Invasive Correction of Postblepharoplasty Lower Eyelid Hollowing Using Hyaluronic Acid: A 5-case Series.Plastic and reconstructive surgery. Global open · 2026Article
- Hyaluronic Acid Fillers Versus Polynucleotides for Under-Eye Rejuvenation.Journal of clinical medicine · 2026Review
- Ultrasound-Based Classification of Infraorbital Fat and Groove Patterns: Clinical Implications for Safer Filler Injection.Aesthetic plastic surgery · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Infraorbital groove and hollowness are common aging-related anatomical changes in the periorbital region, leading to a sunken and tired appearance. These conditions are caused by the progressive loss of volume in the deep fat pads, including the sub-orbicularis oculi fat (SOOF) and malar fat, along with skin thinning and decreased elasticity. Filler injections, particularly hyaluronic acid-based fillers, are the preferred treatment to restore volume and smooth the under-eye area. Proper diagnosis, understanding of anatomical variations, and accurate injection techniques are essential to avoid complications and achieve natural, esthetically pleasing outcomes. Treatments should consider the patient's unique anatomy and potential adjunctive procedures to ensure balanced and harmonious facial rejuvenation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.