Evidence map›Paper›PMID 40003619›Full record

ReviewLife (Basel, Switzerland)2025

A Review of the Impact of Gestational Diabetes on Fetal Brain Development: An Update on Neurosonographic Markers During the Last Decade.

Efthymios Oikonomou, Christos Chatzakis, Sofoklis Stavros, Anastasios Potiris, Konstantinos Nikolettos, Sotirios Sotiriou, Ekaterini Domali, Nikolaos Nikolettos, Alexandros Sotiriadis, Angeliki Gerede

Abstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Observational
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Efthymios OikonomouUnit of Maternal-Fetal-Medicine, Department of Obstetrics and Gynecology, Medical School, Democritus University of Thrace, GR-68100 Alexandroupoli, Greece.ORCID 0009-0005-2177-953X
Christos ChatzakisSecond Department of Obstetrics and Gynecology, Medical School, Aristotle University of Thessaloniki, GR-54124 Thessaloniki, Greece.ORCID 0000-0002-5895-6887
Sofoklis StavrosThird Department of Obstetrics and Gynecology, Medical School, National and Kapodistrian University of Athens, GR-11527 Athens, Greece.
Anastasios PotirisThird Department of Obstetrics and Gynecology, Medical School, National and Kapodistrian University of Athens, GR-11527 Athens, Greece.ORCID 0000-0001-7716-1521
Konstantinos NikolettosUnit of Maternal-Fetal-Medicine, Department of Obstetrics and Gynecology, Medical School, Democritus University of Thrace, GR-68100 Alexandroupoli, Greece.
Sotirios SotiriouDepartment of Embryology, Faculty of Medicine, School of Health Sciences, University of Thessaly, GR-41334 Larissa, Greece.
Ekaterini DomaliFirst Department of Obstetrics and Gynecology, Medical School, National and Kapodistrian University of Athens, GR-11527 Athens, Greece.ORCID 0000-0001-8899-3040
Nikolaos NikolettosUnit of Maternal-Fetal-Medicine, Department of Obstetrics and Gynecology, Medical School, Democritus University of Thrace, GR-68100 Alexandroupoli, Greece.
Alexandros SotiriadisSecond Department of Obstetrics and Gynecology, Medical School, Aristotle University of Thessaloniki, GR-54124 Thessaloniki, Greece.ORCID 0000-0003-0876-5596
Angeliki GeredeUnit of Maternal-Fetal-Medicine, Department of Obstetrics and Gynecology, Medical School, Democritus University of Thrace, GR-68100 Alexandroupoli, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gestational diabetes mellitus (GDM) is a prevalent medical complication in pregnancy that is rapidly escalating worldwide, with epidemic implications. This systematic review aims to identify fetal brain changes using neurosonography and pinpoint potential markers for the early diagnosis of GDM. We conducted a literature search from 6 January 2013 to 4 September 2024 to identify studies examining fetal brain development using ultrasound in pregnancies affected by GDM compared to uncomplicated pregnancies. The outcome measures included the cavum septum pellucidum (CSP), corpus callosum (CC), lateral ventricle (LV), cisterna magna (CM), transcerebellar diameter (TCD), cerebral fissures (CF), and others. For pregnancies affected by GDM, results were reported. Five studies were included. The findings suggest that the width of the CSP was larger in fetuses of mothers with GDM compared to the control group, and the mean widths of LVs were also larger in the fetuses of diabetic mothers compared to the control group. The influence of GDM on fetal brain development as assessed by neurosonography necessitates thorough investigation in future studies.

Indexed as

caveum setum pellucidifetal braingestational diabeteslateral ventricle

Identifiers

PMID40003619
PMCPMC11856126

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.