Evidence map›Paper›PMID 40003618›Full record

ReviewLife (Basel, Switzerland)2025

Innovative Diagnostic Approaches and Challenges in the Management of HIV: Bridging Basic Science and Clinical Practice.

Mohd Afzal, Shagun Agarwal, Rabab H Elshaikh, Asaad M A Babker, Einas Awad Ibrahim Osman, Ranjay Kumar Choudhary, Suresh Jaiswal, Farhana Zahir, Pranav Kumar Prabhakar, Anass M Abbas and 2 more

Abstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mohd AfzalDepartment of Medical Laboratory Technology, Arogyam Institute of Paramedical & Allied Sciences (Affiliated to H.N.B.Uttarakhand Medical Education University), Roorkee 247661, Uttarakhand, India.ORCID 0009-0004-0548-3379
Shagun AgarwalShagun Agarwal, School of Allied Health Sciences, Galgotias University, Greater Noida 203201, Uttar Pradesh, India.
Rabab H ElshaikhDepartment of Medical Laboratory Sciences, College of Applied & Health Sciences, A' Sharqiyah University, Ibra 400, Oman.
Asaad M A BabkerDepartment of Medical Laboratory Sciences, College of Health Sciences, Gulf Medical University, Ajman 4184, United Arab Emirates.ORCID 0000-0002-5022-5676
Einas Awad Ibrahim OsmanDepartment of Medical Laboratory Sciences, College of Applied & Health Sciences, A' Sharqiyah University, Ibra 400, Oman.
Ranjay Kumar ChoudharyDepartment of Medical Laboratory Technology, Amity Medical School, Amity University Haryana, Gurugram 122412, HR, India.
Suresh JaiswalSchool of Health & Allied Sciences, Pokhara University, Pokhara 33700, Nepal.ORCID 0000-0001-5684-6994
Farhana ZahirDepartment of Biology, College of Science, Qassim University, Buraidah 51452, Saudi Arabia.
Pranav Kumar PrabhakarParul Institute of Applied Sciences & Research and Development Cell, Parul University, Gujarat 391760, Vadodara, India.ORCID 0000-0001-8130-1822
Anass M AbbasDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka 72388, Saudi Arabia.
Manar G ShalabiDepartment of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka 72388, Saudi Arabia.ORCID 0000-0003-4921-2162
Ashok Kumar SahDepartment of Medical Laboratory Sciences, College of Applied & Health Sciences, A' Sharqiyah University, Ibra 400, Oman.ORCID 0000-0002-7762-4351

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human Immunodeficiency Virus (HIV) remains a major public health challenge globally. Recent innovations in diagnostic technology have opened new pathways for early detection, ongoing monitoring, and more individualized patient care, yet significant barriers persist in translating these advancements into clinical settings. This review highlights the cutting-edge diagnostic methods emerging from basic science research, including molecular assays, biosensors, and next-generation sequencing, and discusses the practical and logistical challenges involved in their implementation. By analyzing current trends in diagnostic techniques and management strategies, we identify critical gaps and propose integrative approaches to bridge the divide between laboratory innovation and effective clinical application. This work emphasizes the need for comprehensive education, supportive infrastructure, and multi-disciplinary collaborations to enhance the utility of these diagnostic innovations in improving outcomes in patients with HIV.

Indexed as

biosensing techniquesCRISPRHIV diagnosisinnovationpoint-of-care systems

Identifiers

PMID40003618
PMCPMC11856619

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.