ArticleLife (Basel, Switzerland)2025
Global DNA Methylation and DNA Methyltransferase Status Among Cigarette Smokers in Saudi.
Article in Life (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
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2 authors.
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Abstract
Smoking is a serious public health concern worldwide. It is a common environmental factor causing epigenetic alterations. This study aimed to explore the effect of smoking on DNA methylation by quantifying global DNA methylation, measuring the concentrations of plasma DNA methyltransferases (DNMT1, DNMT3A, and DNMT3B) among cigarette smokers in Saudi, and comparing these results with those of nonsmokers. Whole blood specimens were collected from Saudi cigarette smokers (n = 36) and non-smokers as controls (n = 36). Global DNA alteration was determined by a 5-methylation Cytosine (5-mC) colorimetric assay, and the concentration of DNMT proteins was measured by enzyme-linked immunosorbent assay (ELISA). DNA hypomethylation was found in smokers compared with controls (
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